Interactive Tools

Choosing First-Line Antiretroviral Therapy


Source: When to Start, What to Use: A Master Class in the Use of First-Line Antiretroviral Therapy


Considering the efficacy, safety, and tolerability factors in determining the appropriate antiretroviral components for your patient’s initial HAART regimen?

 

This tool enables you to review data from controlled studies on the DHHS and IAS-USA preferred antiretroviral regimens for initial antiretroviral therapy. You can also view a convenient graphical summary of the key data from those studies and print the data and/or download corresponding slides.


Format: Adobe Flash (.swf) | File size: 140 KB | Date posted: 12/6/2007


Drug-Drug Interactions Tool: From the CME-certified program Managing Drug-Drug Interactions in the Changing Landscape of HIV


Source: Managing Drug-Drug Interactions in the Changing Landscape of HIV


Faculty:

 
  • Charles W. Flexner, MD
  • Paul Pham, PharmD, BCPS
This interactive tool will enable readers to select a specific antiretroviral agent from a listing of all FDA-approved agents, and either:
  • Display and print a report of the interactions between this drug and other antiretroviral agents and commonly prescribed concomitant medications, or
  • Select multiple concomitant agents from a listing of those most commonly used by HIV-infected patients, and create a report on any interactions between the selected antiretroviral agents and other non-antiretroviral medications.
Data last updated May 15, 2008.

Format: Adobe Flash (.swf) | File size: 134 KB | Date posted: 5/15/2007


Drug-Drug Interactions in HIV-Infected Patients: A Downloadable Tool for Mobile Devices

This unique downloadable tool for Palm and Pocket PC/Windows Mobile handheld devices allows you to:

  • Search for interactions between antiretrovirals and other medications frequently prescribed for HIV-infected patients
  • Stay up-to-date on pharmacokinetic interactions for the most recently approved antiretroviral agents, including fixed-dose coformulations
  • Review contraindications and potential interactions, adjusted for the impact of ritonavir boosting on specific interactions
  • Receive recommendations on how to resolve contraindications or manage interactions
  • Look up interactions by drug brand names and/or generic names

Tool Version 1.2.  Data last updated May 15, 2008.

 

Download to Hand-held Devices

DOWNLOADABLE FORMATS

Pocket PC / Windows Mobile executable

Format: Pocket PC | File size: 15.41 MB

  • Device Compatibility
    • Pocket PC 2003/Windows Mobile 5
    • Touchscreen required
    • 3.7 MB available memory
  • PC Compatibility
    • Windows 2000 or later
    • Microsoft ActiveSync
  • Instructions
    • Connect device to PC and start ActiveSync
    • Download EXE to PC
    • Run EXE and follow onscreen instructions
Pocket PC / Windows Mobile zipped file

Format: Pocket PC | File size: 2.87 MB

  • Connect device to PC and start ActiveSync
  • Download zip file to PC
  • Extract files
  • Run EXE file
Palm OS executable

Format: Palm | File size: 3.96 MB

  • Device Compatibility
    • Color Palm, minimum resolution 320x320 (Zire devices not supported)
    • Palm OS 4 or later
    • 3.7 MB available memory
  • PC Compatibility
    • Windows 2000 or later
    • Palm Desktop
  • Instructions:
    • Connect device to PC and start Palm Desktop
    • Download EXE to PC
    • Run EXE
    • HotSync the device
Palm OS executable

Format: Palm | File size: 794 KB

  • Connect device to PC and start Palm Desktop
  • Download zip file to PC
  • Extract files
  • Run EXE file
  • HotSync the device

Lipid Effects of Antiretroviral Therapy


Source: Dyslipidemia and Other Cardiovascular Risk Factors in HIV: Causes, Clinical Significance, and Management Strategies


Understanding the potential for dyslipidemia or other cardiovascular risk factors while determining an appropriate HAART regimen

 

This tool enables you to review data from controlled studies on the lipid effects of recommended antiretroviral regimens for initial therapy as well as ‘switch strategies’ in patients on suppressive antiretroviral therapy.

 

You can also view a convenient graphical summary of the key data from those studies and print the data and/or download corresponding slides.


Format: HTML | Date posted: 1/12/2007


Fine-Tuning Antiretroviral Therapy


Source: Fine-Tuning Antiretroviral Therapy in HIV-Infected Patients With Virologic Suppression: Strategies to Address Toxicity, Convenience, and Quality of Life


Considering switching a virologically suppressive antiretroviral regimen and want to know the key data associated with the specific switch?

 

This tool enables you to select specific switches that have been evaluated in controlled studies and then view a convenient graphical summary of the key data from those studies. You can also print the data and/or download slides.


Format: HTML | Date posted: 12/15/2006


Selecting a Boosted PI for the Treatment-Experienced Patient


Source: Strategies for the Management of Multiclass-Resistant Patients


The tool is designed to provide easy access to data on the characteristics and suitability of the available boosted PIs as potential components of regimens for treatment-experienced patients, using data from prescribing information, clinical studies, and the expert opinion of the author, Joseph J. Eron, Jr, MD


Format: Adobe Flash (.swf) | File size: 76 KB | Date posted: 9/2/2005


Selecting an NRTI Backbone: An Interactive Tool


Source: Optimizing the NRTI Backbone in HIV-Infected Patients Receiving Antiretroviral Therapy


This interactive tool is intended to help the user assess the characteristics of different NRTI backbones, according to criteria that have been selected for their potential relevance in specific clinical settings.


Format: Adobe Flash (.swf) | File size: 35 KB | Date posted: 8/24/2004


Neurologic Manifestations of HIV Infection


Faculty:

Katia Cikurel, MDLydia Estanislao, MDDavid M. Simpson, MD
  • Katia Cikurel, MD
  • Lydia Estanislao, MD
  • David M. Simpson, MD


Source: Neurologic Aspects of HIV/AIDS: New Insights and Management Advances


An Interactive Decision Support Tool and Video Resource

A comprehensive guide to neurologic complications directly related to HIV infection of the central nervous system or to opportunistic diseases and neoplasms resulting from immune dysfunction. Browse the complications by name, or search them by presenting symptoms. Includes extensive video clips illustrating components of the neurologic examination, and classic presentations of specific complications.


Format: Adobe Flash (.swf) | File size: 59 KB | Date posted: 5/10/2004


Balancing the Risks vs the Benefit of HAART


Source: Insulin Resistance and Body Shape Changes in HIV-Infected Patients


This interactive tool allows you to explore the balance between the potential benefits and cardiovascular risks of antiretroviral therapy in the background of various patient and treatment-related risk factors.


Format: Adobe Flash (.swf) | File size: 90 KB | Date posted: 4/22/2004


Impact of Different Interventions on Cardiovascular Risk in HIV-Infected Patients


Source: Cardiovascular Risk Factors and Metabolic Complications in Patients Receiving HAART


An interactive resource that illustrates the impact of different interventions on the 10-year risk of cardiovascular disease in hypothetical patients with different baseline characteristics.


Format: Adobe Flash (.swf) | File size: 47 KB | Date posted: 4/21/2004


Algorithm for Management of Patients with Hyperlipidemia During PI-based Therapy


Source: Cardiovascular Risk Factors and Metabolic Complications in Patients Receiving HAART


An interactive flowchart offering options for the clinical care of HIV-infected patients who experience protease inhibitor-associated hyperlipidemia.


Format: Adobe Flash (.swf) | File size: 15 KB | Date posted: 4/21/2004


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