CCO Treatment Updates
The Great Debate: Treatment of HBV and the Impact on Transplantation
Update on Treatment Guidelines for Chronic Hepatitis B in the Transplant Setting
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Module 1 of 3
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Program Director:
Norah Terrault, MD, MPH
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 Topics covered include:
- Introduction
- Treatment Goals in the Transplant Setting
- Antiviral Options in Pre- and Post-Transplant Setting
- Current Guidelines for Treatment of Patients With Cirrhosis
- Current Guidelines for Treatment of Liver Transplant Recipients with Recurrent HBV Disease
Learning Objectives
Upon completion of this activity, participants should be able to:
Describe optimal treatment for chronic hepatitis B in transplant recipients. Review strategies for preventing recurrence of chronic hepatitis B in transplant recipients. Discuss the current status of treatment guidelines for chronic hepatitis B in patients with cirrhosis.
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What is the Optimal Duration of Antiviral Therapy in Patients with Hepatitis B-Related Cirrhosis?
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Module 2 of 3
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Program Director:
Norah Terrault, MD, MPH
 
- Kris V. Kowdley, MD, FACP
- K. Rajender Reddy, MD
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Topics covered include:
- Introduction
- Optimal Duration of Therapy: It Should Be Indefinite, by K. Rajender Reddy, MD
- Indefinite: Natural History
- Indefinite: Candidates for Treatment
- Indefinite: Treatment Endpoints
Learning Objectives
Upon completion of this activity, participants should be able to:
Discuss the current status of treatment guidelines for chronic hepatitis B in patients with cirrhosis. Describe optimal treatment for chronic hepatitis B with cirrhosis. Evaluate strategies for preventing decompensation of chronic hepatitis B.
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Management of HBV Reinfection Following Liver Transplantation
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Module 3 of 3
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Program Director:
Norah Terrault, MD, MPH
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Topics covered include:
- Introduction
- HBV Reinfection After Liver Transplantation
- De Novo HBV Infection/Reactivation
- Diagnosis and Clinical Course
- Drug-Resistant HBV Mutants
Learning Objectives
Upon completion of this activity, participants should be able to:
Describe optimal treatment for chronic hepatitis B in transplant recipients Review strategies for preventing recurrence of chronic hepatitis B in transplant recipients Discuss the current status of treatment guidelines for chronic hepatitis B in patients with cirrhosis
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Interactive Case Challenges
A Middle-Aged Man with Chronic Hepatitis B Awaiting Transplantation
Program Director:
Norah Terrault, MD, MPH
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 Evaluate the treatment options for a patient with hepatitis B infection awaiting liver transplantation Learning Objectives
Upon completion of this activity, participants should be able to:
Describe treatment options for chronic hepatitis B patients with decompensated cirrhosis. Discuss management of HBV patients awaiting liver transplant, including localized treatment of hepatocellular carcinoma lesions. Review data regarding the treatment of hepatitis B patients in the immediate post-transplant period.
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A 43-Year-Old Liver Transplant Recipient with De Novo Hepatitis B Arising after Transplantation
Program Director:
Norah Terrault, MD, MPH
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Test your ability to manage a patient with de novo hepatitis B arising after liver transplantation. Learning Objectives
Upon completion of this activity, participants should be able to:
Discuss the issue of nephrotoxicity in treatment of patients with de novo hepatitis B after liver transplantation Describe data regarding the development of de novo hepatitis B after liver transplantation Review data regarding the management of antiviral treatment for de novo hepatitis B after liver transplantation, including management of drug resistance
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A 56-Year-Old Liver Transplant Recipient with Recurrent Hepatitis B
Program Director:
Norah Terrault, MD, MPH
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Manage the treatment of a patient with recurrent hepatitis B infection after liver transplantation. Learning Objectives
Upon completion of this activity, participants should be able to:
Discuss data regarding the use of hepatitis B immune globulin as prophylaxis against recurrent HBV in the post-transplant period Review data regarding the management of nephrotoxicity in the post-transplant period Describe methods of managing antiviral drug resistance in the post-transplant period
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CCO Slidesets
Management of HBV Reinfection After Liver Transplantation (pdf format)
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Format: Microsoft PowerPoint (.ppt) | File size: 345 KB
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Update on Treatment of Chronic HBV in the Liver Transplant Setting
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Format: Microsoft PowerPoint (.ppt) | File size: 894 KB
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The Optimal Duration of Treatment for Chronic HBV Cirrhosis: Until Endpoints Are Reached
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Format: Microsoft PowerPoint (.ppt) | File size: 413 KB
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The Optimal Duration of Treatment for Chronic HBV Cirrhosis: Indefinite
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Format: Microsoft PowerPoint (.ppt) | File size: 1,000 KB
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Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.
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Jointly sponsored by University of Alabama School of Medicine and Clinical Care Options, LLC.
Nursing CE provided through the cosponsorship of Medical Education Collaborative and Clinical Care Options, LLC.
Contact Info
Educational grant provided by:
Educational grants support only the CME-certified components of this program.
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