Conference Track

Gastrointestinal Cancer

Source: CCO Independent Conference Coverage of the 2007 American Society of Clinical Oncology Annual Meeting*

*CCO is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.


Capsule Summaries

Expert Analysis

Gastrointestinal Cancer


Begin the Expert Analysis

Faculty:

Axel Grothey, MDJohn L. Marshall, MDAlan P. Venook, MD
  • Axel Grothey, MD
  • John L. Marshall, MD
  • Alan P. Venook, MD
Anthony El-Khoueiry, MD
  • Anthony El-Khoueiry, MD

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss the use of biologic agents in the first-line treatment of metastatic colorectal cancer
  • Summarize the use of adjuvant therapy in colorectal cancer
  • Identify factors that contribute to improved prognosis in colorectal cancer
  • Report recent findings in advanced pancreatic cancer
  • Describe results of important new clinical studies relevant to the treatment of hepatocellular carcinoma and esophagogastric cancers

Topics covered include:

  • Cetuximab Plus FOLFIRI Improves Progression-Free Survival in Patents With Previously Untreated Metastatic Colorectal Cancer (CRYSTAL Study)
  • Bevacizumab Added to Standard Combination Therapies Improves Progression-Free Survival in Previously Untreated Metastatic Colorectal Cancer
  • Chemotherapy-Free Interval Not Recommended Following Oxaliplatin-Based Chemotherapy in Treatment of Metastatic Colorectal Cancer
  • Combination Treatment With Active Cytotoxics for Advanced Colorectal Cancer Does Not Prolong Survival vs Sequential Therapy
  • Extending First-Line Bevacizumab Treatment Past First Disease Progression May Improve Survival Outcomes for Patients With Metastatic Colorectal Cancer
  • Cetuximab May Improve Quality of Life When Added to Standard Treatments in Patients With Advanced Colorectal Cancer
  • Biomarkers and Number of Circulating Tumor Cells Predict Treatment Outcome in Patients With Metastatic Colorectal Cancer
  • Perioperative FOLFOX4 Increases Progression-Free Survival in Metastatic Colorectal Cancer Patients With Resectable Liver Metastases
  • Phase III MOSAIC Follow-up Data Confirm Survival Benefit for Adjuvant FOLFOX4 in Stage III Colon Cancer
  • “Western” Diets Associated With Poor Outcomes for Patients With Established, Treated Stage III Colon Cancer
  • Neither Bevacizumab nor Cetuximab Confer Survival Advantage in Advanced Pancreatic Cancer
  • FOLFIRINOX Active as First-Line Therapy for Metastatic Pancreatic Adenocarcinoma
  • Sorafenib Prolongs Survival in Advanced Hepatocellular Carcinoma
  • Preoperative Treatment With 5-Fluorouracil Plus Cisplatin Improves Survival in Resectable Adenocarcinoma of Stomach and Lower Esophagus
  • S-1 Effective as Single-Agent, or Combined With Platinum Drugs, in First-Line Treatment of Advanced Gastric Cancer

CME CREDIT INFORMATION

Release Date: 08/03/07

Expiration Date: 08/02/08


Physicians: maximum of 1.75 AMA PRA Category 1 Credit(s)

Registered Nurses: 1.8 Nursing CE credits

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Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

Educational grants provided by:

Educational grants support only the CME-certified components of this program.

CCO Resources

Gastrointestinal ER

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