Module

Virologic Monitoring in Hepatitis B: Tools for Determining Treatment Candidacy and Response

Source: Virologic Tools for Monitoring Patients With Chronic Hepatitis B

Virologic Monitoring in Hepatitis B: Tools for Determining Treatment Candidacy and Response

Faculty:
Kris V. Kowdley, MD, FACP, FACG, FASGE, AGAF

CME CREDIT INFORMATION

Release Date: 10/31/07

Expiration Date: 10/30/08

Physicians: maximum of 1.25 AMA PRA Category 1 Credit(s)™

Registered Nurses: 1.2 Nursing CE credits

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Learning Objectives

Upon completion of this activity, participants should be able to:

List available virologic tools for monitoring patients with chronic hepatitis B
Discuss the prognostic value of virologic monitoring in assessing the natural history of untreated chronic hepatitis B
Summarize clinical data on the use of virologic endpoints as treatment goals, and the use of virologic monitoring tools in making treatment decisions and assessing response and nonresponse to therapy

Topics covered include:

Introduction
The Role of Virologic Tools in Clinical Practice
HBV DNA Assays
Clinical Significance of HBV Mutations
Clinical Significance of HBV Genotype
Clinical Significance of HBV DNA Titer
Candidacy and Goals for Antiviral Therapy in HBeAg-Positive and HBeAg-Negative Patients
Occurrence and Identification of Resistance to Current HBV Treatment Options
Virologic Markers of Future Resistance
Definitions and Identification of Nonresponse
Role of HBV DNA Monitoring During Treatment to Minimize the Risk of Resistance
The Future of Virologic Monitoring

Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.