60 http://clinicaloptions.com/HIV.aspx en-us ℗ & © 2008 Clinical Care Options CCO is your best source for the newest HIV treatment data. Clinical Care Options Audio highlights from independent conference coverage and other HIV educational programs Clinical Care Options HIV vkeane@clinicaloptions.com Clinical Care OptionsCCO Audio Expert Highlights from the 2008 Retroviruses MeetingAndrew R. Zolopa, MD, discusses data from the STEP trial, which demonstrated that the Ad5 trivalent AIDS vaccine failed to reduce HIV-1 acquisition and may increase the risk of acquisition in an Ad5-immune subgroup of vaccine recipients.http://clinicaloptions.com/hiv_podcast_audio_Retroviruses08_zolopa.mp3Thu, 6 Mar 2008 17:00:00 GMT04:41HIV, AIDS, Zolopa Clinical Care OptionsCCO Audio Expert Highlights from the 2008 Retroviruses MeetingBruce Polsky, MD, discusses the results of an important ACTG study evaluating whether patients who present with an acute opportunistic infection should start antiretroviral therapy immediately or after treatment for the OI.http://clinicaloptions.com/hiv_podcast_audio_Retroviruses08_polsky.mp3Wed, 5 Mar 2008 17:00:00 GMT 07:14HIV, ACTG, Polsky Clinical Care OptionsCCO Audio Expert Highlights from the 2008 Retroviruses MeetingJoel E. Gallant, MD, MPH, reviews highlights of reports on first-line therapies from the 2008 Conference on Retroviruses and Opportunistic Infections.http://clinicaloptions.com/hiv_podcast_audio_Retroviruses08_gallant.mp3Thu, 28 Feb 2008 17:00:00 GMT07:22HIV, Retrovirus, Gallant Clinical Care OptionsCCO Audio Expert Highlights from the 2008 Retroviruses Meeting Joseph J. Eron, Jr., MD, comments on how the "new kids on the block"-maraviroc, raltegravir, and etravirine-have "grown up" with 48-week data being reported at this meeting.http://clinicaloptions.com/hiv_podcast_audio_Retroviruses08_eron.mp3Tue, 26 Feb 2008 17:00:00 GMT 04:25HIV, Eron Clinical Care Options CCO Audio Expert Highlights from the 2008 Retroviruses Meeting Judith S. Currier, MD, MSc, reviews highlights of reports on initial therapy, complications of antiretroviral therapy, and other key topics from the 2008 Retroviruses meeting. http://clinicaloptions.com/hiv_podcast_audio_Retroviruses08_currier.mp3 Fri, 22 Feb 2008 17:00:00 GMT 05:15 HIV, antiretroviral, Currier Clinical Care Options Expert Highlights from the ID Meeting in Chicago Joseph J. Eron, Jr., MD, discusses new data presented in Chicago from the ARTEMIS study comparing the boosted protease inhibitor darunavir/ritonavir with the fixed-dose protease inhibitor lopinavir/ritonavir. http://clinicaloptions.com/hiv_podcast_audio_Chicago07_eron.mp3 Tue, 9 Oct 2007 17:00:00 GMT 4:08 HIV, Daar, retroviruses, AIDS Clinical Care Options Expert Highlights from the ID Meeting in Chicago Trevor Hawkins, MD, reports on efficacy and safety data presented in Chicago on the investigational antiretroviral integrase inhibitors raltegravir and elvitegravir. http://clinicaloptions.com/hiv_podcast_audio_Chicago07_hawkins.mp3 Mon, 8 Oct 2007 17:00:00 GMT 7:57 HIV, Daar, retroviruses, AIDS Clinical Care Options Expert Highlights from the ID Meeting in Chicago Eric S. Daar, MD, discusses reports on viral tropism and tropism assays and the various types of viral entry inhibitors that were presented at the conference in Chicago. http://clinicaloptions.com/hiv_podcast_audio_Chicago07_daar.mp3 Fri, 5 Oct 2007 17:00:00 GMT 12:19 HIV, Daar, retroviruses, AIDS Clinical Care Options Expert Highlights from the ID Meeting in Chicago Joel E. Gallant, MD, MPH, discusses how data presented in Chicago may impact decision making on when to begin antiretroviral therapy. http://clinicaloptions.com/hiv_podcast_audio_Chicago07_gallant.mp3 Thu, 4 Oct 2007 17:00:00 GMT 4:38 HIV, Gallant, retroviruses, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Joel E. Gallant, MD, MPH, reviews new cohort data that may strengthen the growing argument for earlier therapy. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_gallant.mp3 Wed, 29 Aug 2007 17:00:00 GMT 7:28 HIV, Gallant, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Andrew Carr, MD, discusses the long-awaited results of the PREDICT-1 trial as well as other data presented in an oral session on adverse events of ART. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_carr.mp3 Tue, 28 Aug 2007 17:00:00 GMT 7:45 HIV, Carr, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Daniel R. Kuritzkes, MD, summarizes emerging data from presentations about resistance to newer drugs such as CCR5 antagonists, etravirine, and integrase inhibitors. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_kuritzkes.mp3 Thu, 16 Aug 2007 17:00:00 GMT 11:29 HIV, Kuritzkes, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Brian Gazzard, MA, MD, FRCP, describes data from several posters on the treatment of ARV-experienced patients. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_gazzard.mp3 Thu, 23 Aug 2007 17:00:00 GMT 6:10 HIV, Gazzard, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Thomas Quinn, MD, MSc, describes the results of the final reports of the 3 large circumcision trials and the effect of this intervention on preventing HIV acquisition in males. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_quinn.mp3 Tue, 21 Aug 2007 17:00:00 GMT 16:41 HIV, Quinn, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Hoosen Coovadia, MBBS, MD, reviews data investigating strategies to decrease transmission by breastfeeding of HIV from mothers who are HIV infected to their infants. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_coovadia.mp3 Mon, 20 Aug 2007 17:00:00 GMT 5:24 HIV, Coovadia, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Vicente Soriano, MD, PhD, provides an overview of several presentations that address the treatment of HIV and hepatitis coinfection. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_soriano.mp3 Fri, 17 Aug 2007 17:00:00 GMT 10:12 HIV, Soriano, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Eric S. Daar, MD, summarizes results of several ongoing clinical trials of antiretroviral therapy in both treatment-naive and treatment-experienced patients. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_daar.mp3 Thu, 16 Aug 2007 17:00:00 GMT 9:16 HIV, Daar, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention David A. Cooper, MD, DSc, remarks on presentations addressing the pros and cons of early treatment, both in the developed and developing world. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_cooper.mp3 Wed, 15 Aug 2007 17:00:00 GMT 8:53 HIV, Cooper, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Richard E. Chaisson, MD, discusses new data presented on TB and HIV including such topics as immune reconstitution inflammatory syndrome and combining TB and HIV therapy. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_chaisson.mp3 Tue, 14 Aug 2007 17:00:00 GMT 13:24 HIV, Chaisson, retroviruses, IAS, AIDS. Tuberculosis Clinical Care Options Audio highlights from the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention Joel E. Gallant, MD, MPH, reports on first-line therapy by reviewing posters on this subject, including important updates on GS934, ALERT, BMS-089, and GS903E. http://clinicaloptions.com/hiv_podcast_audio_IAS2007_gallant2.mp3 Thu, 9 Aug 2007 17:00:00 GMT 8:55 HIV, Gallant, retroviruses, IAS, AIDS Clinical Care Options Audio highlights from the 2007 retrovirus meeting in Los Angeles Joel Gallant, MD, MPH, discusses the phase IIb comparison of TMC278, a second generation NNRTI, with efavirenz in antiretroviral-naive patients and notes that this agent may challenge efavirenz in this arena. http://clinicaloptions.com/hiv_podcast_audio_retrovirus2007_gallant.mp3 Fri, 16 Feb 2007 17:00:00 GMT 3:11 HIV, Gallant, retroviruses, NNRTI Clinical Care Options Audio highlights from the 2007 retrovirus meeting in Los Angeles W. David Hardy, MD, discusses the results of phase 3 studies of raltegravir (MK-0518) and maraviroc in triple-class-experienced patients, and highlights the availability of these agents, as well as etravirine, through expanded access programs. http://clinicaloptions.com/hiv_podcast_audio_retrovirus2007_hardy.mp3 Wed, 14 Feb 2007 17:00:00 GMT 3:16 HIV, Hardy, retroviruses Clinical Care Options Audio highlights from the 2007 retrovirus meeting in Los Angeles Bruce Polsky, MD, reviews key presentations on the management of coinfections in HIV-infected patients including TB related testing, morbidity and mortality, impact of unsafe sexual practices on acute HCV infection in MSM and surprising results which may impact the use of entecavir for the treatment of HBV/HIV coinfected patients. http://clinicaloptions.com/hiv_podcast_audio_retrovirus2007_polsky.mp3 Tue, 13 Feb 2007 17:00:00 GMT 10:57 HIV, Polsky, retroviruses, HCV, HBV, Hepatitis, Coinfection Clinical Care Options Audio highlights from the 2007 retrovirus meeting in Los Angeles Judith S. Currier, MD, MSc, reviews data from 2 antiretroviral clinical studies that provide information on strategies to decrease treatment-related lipoatrophy in HIV-infected patients. http://clinicaloptions.com/hiv_podcast_audio_retrovirus2007_currier.mp3 Mon, 12 Feb 2007 17:00:00 GMT 4:25 HIV, Currier, retroviruses, lipoatrophy Clinical Care Options Audio highlights from the 2007 retrovirus meeting in Los Angeles Joseph J. Eron, Jr, MD, notes that there were very few reports on drugs in early clinical development at this meeting and discusses the implications of that for treatment of highly experienced patients. http://clinicaloptions.com/hiv_podcast_audio_retrovirus2007_eron.mp3 Fri, 9 Feb 2007 17:00:00 GMT 3:27 HIV, Eron, retroviruses Clinical Care Options Audio highlights from the San Francisco meeting Sally Hodder, MD, summarizes new data on the novel integrase inhibitor, MK-0518, showing the investigational drug had no discernible effect on lipid levels in a phase II study involving treatment-naive patients. http://clinicaloptions.com/hiv_podcast_audio_sfo2006_hodder.mp3 Tue, 7 Nov 2006 17:00:00 GMT 3:08 HIV, Hodder, retroviruses Clinical Care Options Audio highlights from the San Francisco meeting Donald P. Kotler, MD, discusses diagnosis of the Metabolic Syndrome in people with HIV infection and reports new information from the recent Lipodystrophy Workshop regarding the efficacy of dietary and lifestyle interventions in HIV-infected patients. http://clinicaloptions.com/hiv_podcast_audio_sfo2006_kotler.mp3 Tue, 7 Nov 2006 17:00:00 GMT 5:38 HIV, Kotler, retroviruses Clinical Care Options Audio highlights from the San Francisco meeting Joel E. Gallant, MD, MPH, describes how new cohort data from Spain has contributed to the evolving debate on when is the best time to start antiretroviral therapy in treatment-naive patients. http://clinicaloptions.com/hiv_podcast_audio_sfo2006_gallant.mp3 Tue, 7 Nov 2006 17:00:00 GMT 3:05 HIV, Gallant, retroviruses Clinical Care Options Audio highlights from the IAC meeting in Toronto W. David Hardy, MD, reports short-term safety and efficacy data from phase II studies of maraviroc and vicriviroc, investigational CCR5 antagonists and contenders to be the next novel class of HIV therapeutics to reach clinical practice. http://clinicaloptions.com/hiv_podcast_audio_iac2006_hardy.mp3 Tue, 5 Sep 2006 17:00:00 GMT 5:26 HIV, Hardy, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Joseph J. Eron, Jr., MD, examines data on lopinavir/ritonavir monotherapy and considers the apparent risks and benefits of this experimental treatment simplification strategy compared with conventional use of HAART. http://clinicaloptions.com/hiv_podcast_audio_iac2006_eron.mp3 Fri, 1 Sep 2006 17:00:00 GMT 5:56 HIV, Eron, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Charles van der Horst, MD, explores provocative new reports on the relationship between herpes simplex virus infection and risk of HIV transmission, and their implications for HIV prevention programs. http://clinicaloptions.com/hiv_podcast_audio_iac2006_vanderhorst.mp3 Tue, 29 Aug 2006 17:00:00 GMT 3:17 HIV, van der Horst, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Jrgen K. Rockstroh, MD, considers the implications of a new study from Germany, involving patients with acute HIV infection, for use of antiretroviral therapy in people who present with primary infection. http://clinicaloptions.com/hiv_podcast_audio_iac2006_rockstroh.mp3 Mon, 28 Aug 2006 17:00:00 GMT 4:01 HIV, Rockstroh, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Dr. Mark A. Wainberg, explains why he thinks integrase inhibitors may prove to be among the major scientific breakthroughs in management of HIV disease to be reported at the IAC conference. http://clinicaloptions.com/hiv_podcast_audio_iac2006_wainberg2.mp3 Mon, 28 Aug 2006 17:00:00 GMT 6:07 HIV, Wainberg, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Joel E. Gallant, MD, MPH, discusses the findings of a series of major clinical trials evaluating antiretroviral treatment options for use in first-line therapy for patients with HIV infection. http://clinicaloptions.com/hiv_podcast_audio_iac2006_gallant.mp3 Fri, 25 Aug 2006 17:00:00 GMT 6:37 HIV, Gallant, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Sally Hodder, MD, summarizes data from the ALIVE cohort showing that while HAART has reduced the incidence of community-acquired pneumonia in intravenous drug users, this patient group remains at high risk. http://clinicaloptions.com/hiv_podcast_audio_iac2006_hodder.mp3 Tue, 29 Aug 2006 17:00:00 GMT 4:21 HIV, Hodder, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Judith S. Currier, MD, MSc, reviews data from Zambia and Thailand describing outcomes observed in women treated with NNRTI-containing therapy following receipt of nevirapine during pregnancy. http://clinicaloptions.com/hiv_podcast_audio_iac2006_currier.mp3 Wed, 23 Aug 2006 17:00:00 GMT 4:44 HIV, Currier, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Mark A. Wainberg, Co-Chair of the XVI International AIDS Conference, speaks about his hopes for how the Toronto meeting will galvanize support for treatment access programs for people living with HIV/AIDS in resource-limited settings. http://clinicaloptions.com/hiv_podcast_audio_iac2006_wainberg1.mp3 Tue, 22 Aug 2006 17:00:00 GMT 3:14 HIV, Wainberg, retroviruses, IAC Clinical Care Options Audio highlights from the IAC meeting in Toronto Richard E. Chaisson, MD, discusses new evidence from Rio de Janeiro, Brazil, demonstrating that use of HAART plus preventive therapy for TB is more effective than either intervention alone in reducing the incidence of TB among HIV-infected patients. http://clinicaloptions.com/hiv_podcast_audio_iac2006_chaisson.mp3 Tue, 22 Aug 2006 17:00:00 GMT 6:16 HIV, Chaisson, retroviruses, IAC Clinical Care Options Independent highlights from the Retroviruses meeting in Washington D.C. Joel E. Gallant, MD, MPH, discusses the final results of the ACTG 5095 study, and describes promising new data on investigational agents from novel drug classes. http://clinicaloptions.com/hiv_podcast_audio_DC05_gallant.mp3 Mon, 6 Mar 2006 17:00:00 GMT 4:04 HIV, Gallant, retroviruses Clinical Care Options Independent highlights from the Retroviruses meeting in Washington D.C. Sally Hodder, MD summarizes 3 new analyses from the APRICOT study of pegylated interferon plus ribavirin in patients with HIV/HCV coinfection. http://clinicaloptions.com/hiv_podcast_audio_DC05_hodder.mp3 Mon, 27 Feb 2006 17:00:00 GMT 4:15 HIV, HCV, coinfection, Hodder Clinical Care Options Independent highlights from the Retroviruses meeting in Denver Kimberly Y. Smith, MD, MPH, reviews some of the highs and lows of Denver 2006 - progress in drug development contrasted by alarming epidemiological trends among African American gay men. http://clinicaloptions.com/hiv_podcast_audio_Denver06_smith.mp3 Fri, 10 Feb 2006 17:00:00 GMT 3:48 HIV, Smith, retroviruses, drug development, epidemiology Clinical Care Options Independent highlights from the Retroviruses meeting in Denver Joseph J, Eron, Jr., MD, describes promising preliminary data on two candidate agents from a new antiretroviral class, integrase inhibitors: MK-0518 and GS-9137. http://clinicaloptions.com/hiv_podcast_audio_Denver06_eron.mp3 Fri, 10 Feb 2006 17:00:00 GMT 3:48 HIV, Eron, retroviruses, antiretroviral, integrase inhibitors Clinical Care Options Independent highlights from the Retroviruses meeting in Denver Sally Hodder, MD, summarizes provocative data from South Africa demonstrating a reduction in the incidence of tuberculosis in adults and children following the introduction of HAART. http://clinicaloptions.com/hiv_podcast_audio_Denver06_hodder.mp3 Fri, 10 Feb 2006 17:00:00 GMT 3:48 HIV, Hodder, retroviruses, HAART, tuberculosis Clinical Care Options Independent highlights from the Retroviruses meeting in Denver Joel E. Gallant, MD, MPH, discusses the results of SMART, a large international trial investigating CD4-guided intermittent therapy whose recent closure proved to be a major talking point. http://clinicaloptions.com/hiv_podcast_audio_Denver06_gallant.mp3 Fri, 10 Feb 2006 17:00:00 GMT 3:41 HIV, Gallant, retroviruses, CD4-guided fibrosis Clinical Care Options Independent highlights from the ID meeting in Washington, D.C. Donald P. Kotler, MD describes the work of Spanish investigators who have evaluated the clinical utility of a noninvasive method of fibrosis monitoring in HIV/HCV coinfected patients. http://clinicaloptions.com/hiv_podcast_DC05_kotler.mp3 Wed, 8 Feb 2006 17:00:00 GMT 4:03 HIV, Kotler, coinfection, fibrosis Clinical Care Options Independent highlights from the meeting in Dublin Ian M. Sanne, MBBCH, FCP(SA), summarizes the results of phase II studies of TMC125, an investigational NNRTI that demonstrated activity in patients with resistance to existing NNRTI agents. http://clinicaloptions.com/HIV_podcast_dublin05_sanne.mp3 Fri, 3 Feb 2006 17:00:00 GMT 2:48 HIV, Sanne, Dublin, NRTI, resistance Clinical Care Options Independent highlights from the meeting in Dublin W. David Hardy, MD, describes the findings of a trial comparing initial NRTI-sparing therapy compared with standard triple therapy and a study of immunologic responses to first-line therapy with either PI- or NNRTI-based regimens in patients who present with low CD4+ cell counts. http://clinicaloptions.com/HIV_podcast_dublin05_hardy.mp3 Fri, 3 Feb 2006 17:00:00 GMT 3:02 HIV, Hardy, Dublin, NRTI, cell counts Clinical Care Options Independent highlights from the meeting in Dublin Joel E. Gallant, MD, MPH, discusses data presented at EACS on drugs with novel targets in the HIV life cycle: HIV integrase and the CCR5 coreceptor. http://clinicaloptions.com/HIV_podcast_dublin05_gallant.mp3 Thu, 2 Feb 2006 17:00:00 GMT 2:32 HIV, Gallant, Dublin, integrase, CCR5