Treatment Challenges in Myelodysplastic Syndromes

Through a CME-certified educational module and Interactive Case Challenges, CCO's expert faculty members review the latest data on the treatment of myelodysplastic syndromes and explore realistic clinical situations.

CME-certified Module:

Insights Into the Pathogenesis, Classification, and Treatment of Myelodysplastic Syndromes Alan F. List, MD, reviews current clinical trial data regarding the clinical management of patients with MDS.

CME-certified Case Challenges:

Clinical Management of a 69-Year-Old Man With Intermediate-1-Risk Myelodysplastic Syndrome In this Interactive Case Challenge, Azra Raza, MD, and Naomi Galili, PhD, discuss treatment options for a patient with intermediate-risk myelodysplastic syndrome and monosomy of chromosome 7.

	Management of a 69-Year-Old Patient With Deletion 5q Myelodysplastic Syndrome Alan F. List, MD, reviews treatment options for a patient with del(5q) MDS.
	Coming Soon! Treatment of a 52 Year-Old Man with High-Risk MDS Charles A. Schiffer, MD

2007 San Antonio Breast Cancer Symposium

CCO's robust independent coverage of the 2007 SABCS includes downloadable slidesets, Capsule Summaries of key presentations, Expert Analyses on panel discussions, and brief audio Expert Highlights from our faculty members discussing key issues in the treatment of breast cancer highlighted at the conference.

Early Breast Cancer: Endocrine Therapy

Early Breast Cancer: Chemotherapy and Targeted Agents

Metastatic Breast Cancer

Prognosis and Prediction

Practical Answers to Key Clinical Challenges: Optimizing Patient Outcomes in Breast Cancer

In this CME-certified educational module based on the results of a readership survey, Kathy S. Albain, MD; Kathy D. Miller, MD; Hope S. Rugo, MD; and Linda T. Vahdat, MD, discuss breast cancer cases and optimal treatment regimens for patients in the adjuvant, neoadjuvant, and metastatic settings. A downloadable slideset accompanies the module. Click here to begin.

2008 Gastrointestinal Cancers Symposium

CCO's independent coverage of the 2008 Gastrointestinal Cancers Symposium includes 3 CME-certified Conference Reports and an accompanying downloadable slideset focusing on key presentations at the conference.

2007 American Society of Hematology Annual Meeting

CCO's robust independent coverage of the 2007 ASH meeting includes downloadable slidesets, Capsule Summaries of key presentations, Expert Analyses on specific indications, and brief audio Expert Highlights from our faculty discussing the key issues in hematologic malignancies highlighted at the conference. Our major conference tracks include:

• Chronic Myeloid Leukemia
  Charles L. Sawyers, MD; Brian Druker, MD; and Moshe Talpaz, MD
  
  
• Multiple Myeloma
  Kenneth Anderson, MD; Sagar Lonial, MD; and Robert Z. Orlowski, MD, PhD
  
  
• Myelodysplastic Syndromes
  Alan F. List, MD; Azra Raza, MD; and Lewis Silverman, MD
  
  
• Acute Leukemias
  Dan Douer, MD; Stephen J. Forman, MD; and Hagop M. Kantarjian, MD
  
  
• Non-Hodgkin's Lymphoma
  Alexandra M. Levine, MD; Carol S. Portlock, MD; and Julie M. Vose, MD
  
  
• Chronic Lymphocytic Leukemia
  John C. Byrd, MD; Michael J. Keating, MB BS; and Kanti Rai, MD

Melanoma Treatment Update

Through 4 CME-certified educational modules, CCO’s expert faculty members review the latest data on the treatment of melanoma.

Genetics and Molecular Pathogenesis of Melanoma: Current Understanding

Diagnosis and Staging of Melanoma: Evolving Practice

Treatment of Melanoma: Current Best Practice

Exploring New Directions in Melanoma Treatment

6th International Symposium on Translational Research in Oncology

Through 8 CME-certified slidesets, CCO's expert faculty members, including Program Directors Dennis J. Slamon, MD, PhD, and John Crown, MD, MPH, review the latest data based on translational research in oncology that were presented at the International Translational Research in Oncology meeting held in Dublin, Ireland, in October 2007.

Advances in Metastatic Colorectal Cancer: Molecular Pathways, Biomarkers, and Clinical Results

This series of CME-certified Expert Recaps and accompanying downloadable slidesets provides a comprehensive update on the use of targeted treatments and biomarkers to optimize patient outcomes in metastatic colorectal cancer. Developed with Clinical Care Options' expert faculty members, these slidesets are available for use as a self-study resource or in your own presentations.

Adjuvant HER2-Positive Cancer: Integrating Prognostic Tools and Clinical Advances to Optimize Treatment

• Current Clinical Data on Adjuvant Therapy for HER2-Positive Breast Cancer
  In this educational module, Nicholas J. Robert, MD, reviews the biology and testing of HER2, clinical studies evaluating HER2-based adjuvant regimens, adverse effects, and how to use such regimens in clinical practice. Click here to begin.
  
• Estimating Benefit and Prognosis With Adjuvant Therapy for HER2-Positive Breast Cancer
  In this educational module, Peter Ravdin, MD, PhD, discusses approaches to estimating the benefit of adjuvant therapy and determining the prognosis for patients with breast cancer. Click here to begin.
  
• Treatment of a 32-Year-Old Patient With HER2-Positive Breast Cancer
  In this Interactive Case Challenge, Daniel F. Hayes, MD, and Jeffrey B. Smerage, MD, PhD, discuss the adjuvant treatment of a premenopausal patient with HER2-positive breast cancer. Click here to begin.
  
• Treatment of Breast Cancer in a 64-Year-Old Black Female With Multiple Positive Lymph Nodes
  In this Interactive Case Challenge, Linda T. Vahdat, MD, investigates the treatment options available for a 64-year-old black woman with newly diagnosed invasive breast cancer. Click here to begin.
  

CCO Slideset: Assessing Breast Cancer Prognosis and Applications for Clinical Practice

Comprehensive downloadable slideset on novel approaches in cancer immunotherapy. Download slides

• Tumor Immunology: Treatment Approaches With Immunotherapies in Human Cancer
  Review 3 CME-certified modules and a downloadable slideset.
  
  
• Advances in the Treatment of Lymphoproliferative Malignancies: Promising Directions in Mantle Cell Lymphoma, Follicular Lymphoma, and Waldenstrom’s Macroglobulinemia
  Access 4 interactive modules and downloadable slidesets.
  
  
• Optimal Treatment of Locally Advanced/Metastatic Pancreatic Cancer: Current Progress and Future Challenges
  This series includes 2 CME-certified didactic modules and a downloadable slideset.
  
  
• Anthracyclines in the Treatment of Multiple Myeloma: Traditional and Evolving Roles
  Through a CME-certified educational module, CCO's expert faculty review the use of anthracyclines in the treatment of patients with multiple myeloma and help you to apply this information in real-world scenarios through CME-certified interactive case challenges.
  
  
• Imatinib Resistance in the Treatment of Chronic Myeloid Leukemia: Current Management Options and Emerging Therapies
  In this CME-certified educational module, Elias Jabbour, MD; Jorge E. Cortes, MD; and Hagop M. Kantarjian, MD, discuss current and evolving treatments for chronic myeloid leukemia.
  
  
• Proceedings of the 17th International Prostate Cancer Update Meeting
  Noted experts in the field of prostate cancer put the latest findings from this meeting in perspective.
  
  
• Treatment Advances in Multiple Myeloma: Management of Challenging Clinical Scenarios
  This series includes 2 interactive cases that test your ability to manage patients and give you the opportunity to compare your answer with that of others who have taken the test. Be sure to read the introductory educational module for the latest thinking on treatment in this rapidly changing field.
  
  
• Navigating Multiple Pathways: Evolving Options and Future Directions in Targeted Therapies
  In this series of 3 educational modules with accompanying downloadable slidesets, CCO's expert oncology faculty members discuss the use of targeted agents as well as the utility of the tumor microenvironment as a therapeutic target.
  
  
• Management of Recurrent Epithelial Ovarian Cancer: Current Standards and Novel Approaches
  Through 3 virtual presentations and a downloadable slideset, explore the treatment of patients with platinum-sensitive and platinum-resistant ovarian cancer.

Hematologic Malignancies Volume 2, Issue 1, 2007

• Maintenance Therapy With Thalidomide in Patients With Multiple Myeloma by Sagar Lonial, MD
  
• Bortezomib in the Treatment of Patients With Waldenström's Macroglobulinemia by Steven P. Treon, MD, MA, PhD
  
• Magnetic Resonance Imaging vs Metastatic Bone Survey for the Detection of Focal Lesions in Patients With Multiple Myeloma by Noopur Raje, MD
  
• Significance of Complete Responses After Autologous Stem Cell Transplantation in Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma by Craig H. Moskowitz, MD
  
• Lenalidomide Shows High Response Rate in Patients With Relapsed or Refractory B-Cell CLL by Bruce D. Cheson, MD

• 2007 American Society of Hematology Annual Meeting*
  
  
• 2007 San Antonio Breast Cancer Symposium*
  
  
• 2007 ASCO Prostate Cancer Symposium*
  
  
• 2007 American Society of Clinical Oncology Annual Meeting *
  
  
• 2007 Gastrointestinal Cancers Symposium *
  
  
  

*CCO is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.

Research Priorities in Colorectal Cancer: Recommendations of the Scientific Leadership Council in GI Cancer of the Coalition of Cancer Cooperative Groups Colorectal Cancer: Demographics and Screening

• Colorectal Cancer Prevention
• Colorectal Cancer Detection and Diagnosis
• Adjuvant Treatment for Rectal Cancer
• Adjuvant Treatment for Colon Cancer
• Advanced Colorectal Cancer and Novel Therapies

Research Priorities in Non-Small-Cell Lung Cancer

• Barriers to Clinical Trial Accrual and Recommendations for Improvement
• Adjuvant and Neoadjuvant Therapy for Early-Stage NSCLC
• Screening and Imaging in NSCLC
• First-Line and Second-Line Treatment of Advanced Non-Small-Cell Lung Cancer
• Novel Therapeutic Approaches

Cutaneous T-Cell Lymphoma

• Treatment of Early-Stage CTCL in a 56-Year-Old Black Male Patient
• Treatment of a 54-Year-Old Male With Tumor-Stage Mycosis Fungoides
• Treatment of Recurrent Folliculotropic Mycosis Fungoides in a 37-Year-Old Black Female Patient

Topics

• Breast Cancer
• Gastrointestinal Cancer
• General Hematology
• Genitourinary Cancer
• Gynecologic Cancer
• Head and Neck Cancer
• Hematologic Malignancies
• Lung Cancer

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Anthracycline Benefit Observed Only With Topoisomerase IIa Amplification in Patients With HER2-Positive Breast Cancer

Anthracyclines may not provide any additional benefit to patients with HER2-positive breast cancer lacking amplification/overexpression of topoisomerase IIa, according to a retrospective analysis.

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