Precision Skin Cancer Diagnosis: Gene Expression Profiling for Melanoma and cSCC

Early detection and appropriate, risk-adjusted treatment is essential to ensure optimal outcomes for patients diagnosed with skin cancers such as melanoma and cutaneous squamous cell carcinoma (cSCC). Unfortunately, diagnosis of these malignancies can be challenging, and many patients are not diagnosed until later stages of disease. Once a patient is diagnosed, determining their risk status is particularly important, as it has major implications for treatment selection. Failure to appropriately assess patient risk can lead to either over or undertreatment, negatively impacting patient outcomes. In recent years, novel gene expression profiling (GEP) technologies designed to aid in diagnosis and risk assessment have emerged for melanoma and cSCC, and many more are in development. Use of these tests can help dermatology clinicians, including nurse practitioners and physician assistants in early identification of patients with high-risk disease who may require a more aggressive treatment approach.


Program Content


  • Gene Expression Profiling for Melanoma and cSCC
    Precision Skin Cancer Diagnosis: Gene Expression Profiling for Melanoma and cSCC
    Congratulations: You achieved a completion on 04/09/2022

    Released: September 30, 2022

    Expires: September 30, 2023

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Sylvana Brickley, DNP, FNP-BC, DCNP

Lahey Dermatology
Burlington, Massachusetts

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Aaron S. Farberg, MD, FAAD

Medical Director
Derm Texas
Dermatology Research Institute
Assistant Professor
Baylor Scott & White Health System
Dallas, Texas

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Cynthia Griffith, MPAS, PA-C

Physician Assistant University of Texas Southwestern Medical Center
Department of Dermatology
Editor in Chief Journal of Dermatology Physician Assistants
Dallas, Texas

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Sherrif Ibrahim, MD, PhD

Associate Professor of Dermatology
University of Rochester Medical Center
Rochester, New York

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Jointly provided by PCME and Rockpointe.


This activity is supported by an educational grant from Castle Biosciences, Inc.

Castle Biosciences, Inc.