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Phase Ib/II Trial of Ivosidenib + Venetoclax ± Azacitidine in IDH1-Mutated Myeloid Malignancies

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Early-stage results with ivosidenib and venetoclax with or without azacitidine suggest a high CRc with a tolerable safety profile in patients with IDH1-mutated myeloid malignancies

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Supported by educational grants from

AbbVie

Amgen, Inc.

AstraZeneca

Bristol Myers Squibb

Daiichi Sankyo, Inc.

Exelixis

Gilead Sciences, Inc.

GlaxoSmithKline

Ipsen Biopharmaceuticals Inc

Merck Sharp & Dohme Corp.

Novartis Pharmaceuticals Corporation

Pfizer, Inc.

Pharmacyclics LLC an AbbVie Company and Janssen Biotech Inc

Sanofi Genzyme