ProCE Banner Activity


Updates for Community Practice: Expert Guidance on Biomarker-Driven Therapeutic Approaches in Gastrointestinal Cancers


Get up to date with this on-demand webcast from a live event focused on the latest approaches in biomarker testing and targeted therapy for GI cancers.

Nurses: 0.75 Nursing contact hour

Physicians: maximum of 0.75 AMA PRA Category 1 Credit

Pharmacists: 0.75 contact hour (0.075 CEUs)

Released: October 05, 2023

Expiration: October 04, 2024



James M. Cleary

James M. Cleary, MD, PhD

Associate Professor of Medicine
Harvard Medical School
Director of Clinical Research
Gastrointestinal Oncology
Dana-Farber Cancer Institute
Boston, Massachusetts

Provided by

Provided by Clinical Care Options, LLC.

ProCE Banner


Supported by educational grants from Bayer HealthCare Pharmaceuticals Inc. and Merck Sharp & Dohme LLC.

Bayer HealthCare Pharmaceuticals Inc.

Merck Sharp & Dohme, LLC

Target Audience

This educational program is intended for oncologists, nurses, pharmacists, and other healthcare professionals on the multidisciplinary team caring for patients with gastrointestinal cancers.

Program Learning Goal

The goal of this activity is to improve the knowledge and competence of learners to assess new and emerging GI biomarkers and to integrate biomarker findings into the planning of individualized treatments for patients with gastrointestinal malignancies.

Learning Objectives

  • Apply best practices for molecular testing in GI cancers, including the use of tissue-based biomarker testing for evaluation of BRAFV600E, HER2, HER3, BRCA1/2, FGFR2, IDH1, and histology-agnostic markers

  • Discuss with patients the available clinical data and how predictive biomarkers can be used to guide therapy decisions in GI cancers

  • Plan individualized therapeutic strategies for patients with GI malignancies based on predictive biomarker assessment

  • Identify patients with GI malignancies who are appropriate for enrollment on ongoing clinical trials investigating novel biomarker-driven treatment strategies in GI malignancies


Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

James M. Cleary, MD, PhD

Associate Professor of Medicine
Harvard Medical School
Director of Clinical Research
Gastrointestinal Oncology
Dana-Farber Cancer Institute
Boston, Massachusetts

James M. Cleary, MD, PhD: consultant/advisor/speaker: Blueprint, Incyte; researcher: Apexigen, Arcus, AstraZeneca, Bayer, Bristol Myers Squibb, Esperas Pharma, GlaxoSmithKline, Merck, Merus, Servier.

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose, except Kristi K. Orbaugh as noted below.

Kristi K. Orbaugh, MSN, NP, AOCNP: consultant/advisor/speaker: AstraZeneca, Bristol Myers Squibb, CTI, DSI, Gilead, Lilly, MorphoSys, Pfizer.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.75 hours. To successfully complete this activity and receive credit, learners must follow these steps during the period from October 05, 2023, through October 04, 2024:

  1. Login or Sign Up for an account by clicking at the top of this page.
  2. Read the target audience, learning objectives, and faculty disclosures.
  3. View and study the content in its entirety.
  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.


The program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


Joint Accreditation Statement

A logo for a companyDescription automatically generated with low confidence

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


Physician Continuing Medical Education
CCO designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development
The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.75 contact hours.

Continuing Pharmacy Education
CCO designates this continuing education activity for 0.75 contact hours (0.075 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number - JA4008176-0000-23-246-H01-P.

Type of Activity: Application

Upon successfully completing the post-test with a score of 65 or better and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.