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CodeBreaK101: Phase Ib/II Study With Sotorasib + RMC-4630, an SHP2 Inhibitor, in Advanced NSCLC and Other Solid Tumors With KRAS p.G12C Mutation

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Sotorasib plus RMC-4630 appears well-tolerated with promising response rates for previously treated patients with advanced NSCLC and a KRAS p.G12C mutation.

Released: August 12, 2022

Expiration: August 11, 2023

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Supported by educational grants from

Amgen, Inc.

Genentech, a member of the Roche Group

Merck Sharp & Dohme Corp.

Turning Point Therapeutics Inc