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EV-302/KEYNOTE-A39: Phase III Trial of Enfortumab Vedotin + Pembrolizumab vs Chemotherapy in Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma

Conference Coverage

In this randomized phase III trial, enfortumab vedotin plus pembrolizumab demonstrated statistically and clinically significant improvements in PFS and OS vs chemotherapy in patients with previously untreated locally advanced or metastatic urothelial cancer. 

Released: October 30, 2023


Provided by

Provided by Clinical Care Options, LLC.

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Supported by educational grants from AstraZeneca, Bristol Myers Squibb, Daiichi Sankyo, Inc., Exelixis, Inc., Gilead Sciences, Inc., Lilly and Regeneron Pharmaceuticals, Inc.


Bristol Myers Squibb

Daiichi Sankyo, Inc.

Exelixis, Inc.

Gilead Sciences, Inc.


Regeneron Pharmaceuticals, Inc