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Phase III GEM2014MAIN: Maintenance With Ixazomib + Len/Dex vs Len/Dex After VRd + ASCT in Newly Diagnosed MM

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The addition of ixazomib to lenalidomide/dexamethasone maintenance did not confer a PFS benefit in any subgroup of patients following the completion of ASCT, likely due to dose reductions/discontinuation associated with toxicity.

Released: December 14, 2021

Expiration: December 13, 2022

No longer available for credit.


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Daiichi Sankyo, Inc.


Incyte Corporation

Jazz Pharmaceuticals, Inc.

Merck Sharp & Dohme Corp.

Novartis Pharmaceuticals Corporation