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Combination Immunotherapy and Chemotherapy Regimens in NSCLC: Clinical Practice Recommendations for Oncology Nurses


Watch this archived webcast of a live presentation by nurse expert Rasheda Persinger, MSN, AGNP-C, AOCNP, on key nursing considerations when caring for patients with NSCLC receiving an immune checkpoint inhibitor in combination with chemotherapy.

Nurses: 1.00 Nursing contact hour

Released: October 05, 2023

Expiration: October 04, 2024



Rasheda Persinger

Rasheda Persinger, MSN, AGNP-C, AOCNP

Medical Oncology Lead Nurse Practitioner
Sidney Kimmel Cancer Center Sibley Memorial Hospital
Johns Hopkins System
Washington, DC

Provided by

Provided by Clinical Care Options, LLC

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This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.

Regeneron Pharmaceuticals, Inc

Target Audience

This program is intended for oncology nurses and other multidisciplinary care team members involved in the treatment of patients with non-small-cell lung cancer.

Program Learning Goal

The goal of this activity is to improve the knowledge, confidence, and competence of oncology nurses and other healthcare professionals in caring for patients with non-small-cell lung cancer receiving combination chemotherapy and immune checkpoint inhibitor therapy.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify the mechanism of action of immune checkpoint inhibitors used to treat NSCLC

  • Educate patients and colleagues about the rationale and key data highlights supporting the use of chemoimmunotherapy regimens in NSCLC

  • Employ a holistic approach to administering chemoimmunotherapy in NSCLC that takes into account patients’ health and preferences and educates patients on safety issues

  • Manage adverse events associated with chemoimmunotherapy regimens for NSCLC while maintaining optimal benefit from these agents


Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Rasheda Persinger, MSN, AGNP-C, AOCNP

Medical Oncology Lead Nurse Practitioner
Sidney Kimmel Cancer Center Sibley Memorial Hospital
Johns Hopkins System
Washington, DC

Rasheda Persinger, MSN, AGNP-C, AOCNP: consultant/advisor/speaker: Amgen, AstraZeneca, Guardant Health, Mirati. 

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 1 hour. To successfully complete this activity and receive credit, learners must follow these steps during the period from October 05, 2023, through October 04, 2024:

  1. Login or Sign Up for an account by clicking at the top of this page
  2. Read the target audience, learning objectives, and faculty disclosures
  3. View and study the content in its entirety
  4. Submit answers to the post-test questions and evaluation questions online

You must receive a test score of 65 or better and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.


This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


Joint Accreditation Statement
Joint AccreditationIn support of improving patient care, Clinical Care Options, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 


Nursing Continuing Professional Development
The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1 contact hour.