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Tumor Treating Fields + Immune Checkpoint Inhibition in Metastatic NSCLC After Platinum Failure: Phase III LUNAR Subgroup Analysis by PD-L1 Expression

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This exploratory post hoc analysis of the phase III LUNAR trial suggests that the survival benefit with TTFields + ICI therapy after progression on/after platinum-based chemotherapy is more pronounced in patients with PD-L1–positive (TPS ≥1%) metastatic NSCLC vs those with PD-L1–negative disease.

Released: September 14, 2023

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Supported by educational grants from AstraZeneca, Daiichi Sankyo, Inc, Gilead Sciences Inc., and Regeneron Pharmaceuticals, Inc.

AstraZeneca

Daiichi Sankyo, Inc.

Gilead Sciences, Inc.

Regeneron Pharmaceuticals, Inc