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Next-Generation Endocrine Therapies for ER+/HER2- Breast Cancer Care: Key Takeaways From Our Recent Symposium in San Antonio

Clinical Thought

Get up to date with experts’ key takeaways on next-generation endocrine therapies for ER-positive/HER2-negative breast cancer, including guidance on ESR1 mutation testing, use of oral SERDs in patients with ESR1 mutations, and other endocrine therapies on the horizon.

Released: December 20, 2023

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Faculty

Erika P. Hamilton

Erika P. Hamilton, MD

Director, Breast Cancer Research Program
Sarah Cannon Research Institute
Tennessee Oncology
Nashville, Tennessee

Kevin Kalinsky

Kevin Kalinsky, MD, MS

Professor of Medicine
Director, Glenn Family Breast Center
Winship Cancer Institute
Emory University
Atlanta, Georgia

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Provided by Clinical Care Options, LLC

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Supporters

Supported by an educational grant from AstraZeneca.

AstraZeneca

Disclosure

Primary Author

Erika P. Hamilton, MD

Director, Breast Cancer Research Program
Sarah Cannon Research Institute
Tennessee Oncology
Nashville, Tennessee

Erika P. Hamilton, MD: researcher (paid to institution): Abbvie, Acerta Pharma, Accutar Biotechnology, ADC Therapeutics, AKESOBIO Australia, Amgen, Aravive, ArQule, Artios, Arvinas, AstraZeneca, AtlasMedx, BeiGene, Black Diamond, Bliss BioPharmaceuticals, Boehringer Ingelheim, Cascadian Therapeutics, Clovis, Compugen, Context Therapeutics, Cullinan, Curis, CytomX, Daiichi Sankyo, Dana Farber Cancer Inst, Dantari, Deciphera, Duality Biologics, eFFECTOR Therapeutics, Ellipses Pharma, Elucida Oncology, EMD Serono, FujiFilm, G1 Therapeutics, H3 Biomedicine, Harpoon, Hutchinson MediPharma, Immunogen, Immunomedics, Incyte, Infinity Pharmaceuticals, InventisBio, Jacobio, Karyopharm, K-Group Beta, Kind Pharmaceuticals, Leap Therapeutics, Lilly, Loxo Oncology, Lycera, Mabspace Biosciences, Macrogenics, MedImmune, Mersana, Merus, Millennium, Molecular Templates, Novartis, Nucana, Olema, OncoMed, Onconova Therapeutics,Oncothyreon, ORIC Pharmaceuticals, Orinove, Orum Therapeutics, Pfizer, PharmaMar, Pieris Pharmaceuticals, Pionyr Immunotherapeutics, Plexxikon, Prelude Therapeutics, Profound Bio, Radius Health, Regeneron, Relay Therapeutics, Repertoire Immune Medicine, Rgenix, Roche/Genentech, SeaGen, Sermonix Pharmaceuticals, Shattuck Labs, StemCentRx, Sutro, Syndax, Syros, Taiho, TapImmune, Tesaro, Tolmar, Torque Therapeutics , Treadwell Therapeutics, Verastem, Zenith Epigenetics, Zymeworks; consultant/advisor (paid to institution): AstraZeneca, Daiichi Sankyo, Ellipses Pharma, Gilead Sciences, Greenwich LifeSciences, Janssen, Jazz Pharmaceuticals, Lilly, Loxo, Medical Pharma Services, Mersana, Novartis, Olema Pharmaceuticals, Orum Therapeutics, Pfizer, Relay Therapeutics, Roche/Genentech, SeaGen, Stemline Therapeutics, Theratechnologies, Tubulis, Verascity Scine, Zentalis Pharmaceuticals.

Kevin Kalinsky, MD, MS

Professor of Medicine
Director, Glenn Family Breast Center
Winship Cancer Institute
Emory University
Atlanta, Georgia

Kevin Kalinsky, MD, MS: consultant/advisor/speaker: AstraZeneca, Daiichi Sankyo, Genentech/Roche, Immunomedics, Menarini, Merck, Mersana, Myovant Sciences, Puma Biotechnology, Seattle Genetics, Silicon Biosystems, Takeda.