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My Thoughts on the Use of PARP Inhibitor Plus AR-Signaling Inhibitor Combinations for Our Patients With mCRPC

Clinical Thought

In this expert commentary, Rana R. McKay, MD, offers her perspective on how the latest approvals of combination therapy with a PARP inhibitor and an AR-signaling inhibitor will affect treatment choices for patients with mCRPC.

Released: September 27, 2023

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Faculty

Rana R. McKay

Rana R. McKay, MD

Associate Professor of Medical Oncology and Urology
Associate Director, Clinical Sciences
Co-Lead, Genitourinary Malignancies Program
Moores Cancer Center
University of California San Diego
La Jolla, California

Provided by

Provided by Clinical Care Options, LLC., in partnership with ZERO Prostate Cancer

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Supporters

Supported by educational grants from AstraZeneca, Bayer HealthCare Pharmaceuticals Inc., Janssen Biotech, Inc. administered by Janssen Scientific Affairs, LLC, Lilly, Merck Sharp & Dohme Corp., and Novartis.

AstraZeneca

Bayer HealthCare Pharmaceuticals Inc.

Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC

Lilly

Novartis

Partners

ZERO Prostate Cancer

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Disclosure

Primary Author

Rana R. McKay, MD

Associate Professor of Medical Oncology and Urology
Associate Director, Clinical Sciences
Co-Lead, Genitourinary Malignancies Program
Moores Cancer Center
University of California San Diego
La Jolla, California

Rana R. McKay, MD: consultant/advisor/speaker: AstraZeneca, Aveo, Bristol-Myers Squibb, Bayer, Calithera, Caris, Dendreon, Eisaix, Exelixis, Johnson & Johnson, Lilly, Myovant, Merck, Novartis, Pfizer, Sanofi, Seagen, Sorrento, Telix, Tempus; research funding (paid to institution): Artera, Bayer, BMS, Exelixis, AstraZeneca, Oncternal, Tempus.