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Controlling Resistant Hypertension

CE / CME

Pressure Points in Resistant Hypertension: Pioneering New Pathways to Control the Uncontrollable

Physician Assistants/Physician Associates: 1.50 AAPA Category 1 CME credits

Nurse Practitioners/Nurses: 1.50 Nursing contact hours

Physicians: maximum of 1.50 AMA PRA Category 1 Credits

Released: September 25, 2025

Expiration: September 24, 2026

Pretest

Progress
1 2 3
Course Completed
Please answer the questions below.
1.

Which of the following patients most likely has true resistant HTN? 

2.

A 64-yr-old man with CKD and resistant HTN has a BP of 158/92 mm Hg on amlodipine, chlorthalidone, and valsartan. He was unable to tolerate spironolactone because of gynecomastia. Labs demonstrate a suppressed renin and elevated aldosterone level.  Which potential therapeutic approach, based on ongoing studies, is likely to best target the underlying mechanism?

3.

A 68-yr-old woman with resistant HTN, stage 2 CKD (eGFR 65 mL/min), and persistent hypokalemia (K⁺ 3.2 mmol/L) has an elevated BP on an ACEi, CCB, and thiazide diuretic. Based on clinical trial data, which treatment approach is likely to be most effective?