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Heart Failure: Evolving Treatment Choices and New Guidance


Heart Failure: Evolving Treatment Choices and New Guidance will address the rapidly shifting HF management paradigm, providing information about the most recent evidence-based recommendations for managing HFrEF, newer approved agents, and those agents for which approval is anticipated soon, as well as agents in late-stage investigation for the management of HFpEF.

Welcome and Introduction
Newer Agents for the Management of HFrEF: Efficacy and Safety
Agents in Late-Stage Development for the Management of HF
Heart Failure Decision Pathway: 2022 Update
Q&A Session and Activity Roundup

Physicians: Maximum of 1.00 Medical Knowledge MOC point

Physicians: Maximum of 1.00 AMA PRA Category 1 Credit™

Released: October 24, 2022

Expiration: October 23, 2023

No longer available for credit.



John Ryan

John Ryan, MD, MB, BCH, BAO

Professor of Medicine
Division of Cardiovascular Medicine
University of Utah
Salt Lake City, Utah

Muthiah Vaduganathan

Muthiah Vaduganathan, MD, MPH

Co-Director, Center for Cardiometabolic Implementation Science
Brigham and Women’s Hospital
Harvard Medical School
Boston, MA

Provided by

Jointly provided by the Potomac Center for Medical Education and Rockpointe

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This program is supported by an educational grant from Merck & Co, Inc.

Merck & Co., Inc.

Target Audience

The intended audience for this educational initiative is cardiologists, who are clinicians responsible for the management of patients with heart failure.

Learning Objectives

At the conclusion of this education, participants should be able to:

  • Evaluate the evidence showing the efficacy and safety of newer agents approved for the management of HFrEF

  • Describe the mechanism of action of and efficacy and safety data for agents in late-stage development for the management of heart failure

  • Develop individualized evidence-based management plans for patients with heart failure that are based on recommendations from the 2021 update to the ACC heart failure decision pathway


Potomac Center for Medical Education (PCME) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other relevant professional organizations, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous.

All persons in a position to control the content of an accredited continuing education program provided by the Potomac Center for Medical Education are required to disclose to PCME all financial relationships with any ineligible company within the past 24 months. All financial relationships reported are identified as relevant and mitigated by PCME in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by PCME to assure objectivity and that the activity is free of commercial bias. All relevant financial relationships have been mitigated by PCME.

Faculty, Authors, and Content Developers
The faculty, authors, and content developers reported the following relevant financial relationships with ineligible companies:

John J. Ryan, MD, MD, BCH, BAO: Has no relevant financial relationships

Muthiah Vaduganathan, MD, MPH: Consulting Fee: American Regent, Amgen, AstraZeneca, Bayer AG, Baxter Healthcare, Boehringer Ingelheim, Cytokinetics, Lexicon Pharmaceuticals, Novartis, Pharmacosmos, Relypsa, Roche Diagnostics, Sanofi, Tricog Health; Contracted Research: Amgen, AstraZeneca, Boehringer Ingelheim, Roche Diagnostics, Bayer, Novartis, Occlutech, Galmed, and Impulse Dynamics; Speakers' Bureau: Novartis, Roche Diagnostics

Planners and Managers
The planners and managers reported the following relevant financial relationships with ineligible companies: 

Terry Glauser, MD, MPH: Has no relevant financial relationships

Content Reviewers
The content reviewers reported the following relevant financial relationships with ineligible companies: 

Katie Propst, PhD: Has no relevant financial relationships

Instructions for Credit

There is no fee for this activity. To receive credit, participants must take the pre-test, view this CME/MOC activity in its entirety, and then complete the post-test, with a score of 70% or better, and evaluation. The estimated time for completion of this activity is 1 hour. To receive their certificates, participants must demonstrate mastery of the presented material via the post-test. Participant is allowed to take the post-test multiple times.

Disclosure of Unlabeled Use

The contents of some CME activities may contain discussions of non-approved or off-label uses of some agents mentioned. Please consult the prescribing information for full disclosure of approved uses.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the ACCME to provide continuing medical education for physicians.

The Potomac Center for Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For questions regarding CME/MOC credit or the evaluation, please email


Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
To recieve CME credit and/or MOC points, you MUST pass the post-test and complete the evaluation. For ABIM MOC points, your information will be shared with the ABIM through PCME's ACCME Program and Activity Reporting System (PARS). Please allow 6-8 weeks for your MOC points to appear on your ABIM records. 

Through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, Heart Failure: Evolving Treatment Choices and New Guidance has met the requirements as a Lifelong Learning CME Activity(apply toward general CME requirement) for the following ABMS Member Boards:

ABMS Lifelong Learning CME Activity
Family Medicine