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CME

Selected FXR Agonist PBC Studies: Conference Coverage of AASLD

Conference Coverage
Clinical Thought

Read my insights on exciting new data from AASLD 2023 for people with PBC, including a late-breaking study of an FXR agonist plus a fibrate, real-world outcomes in patients treated with an FXR agonist as second-line therapy, and lessons learned from PBC outcomes trials.

Physicians: Maximum of 0.25 AMA PRA Category 1 Credit

Released: December 20, 2023

Expiration: December 19, 2024

No longer available for credit.

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Faculty

Kris V. Kowdley

Kris V. Kowdley, MD, FAASLD, FACP, FACG

Professor, Elson S. Floyd College of Medicine
Washington State University
Director, Liver Institute Northwest
Seattle, Washington

Provided by

Provided by Clinical Care Options, LLC

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Supporters

Supported by an educational grant from CymaBay Therapeutics.

CymaBay Therapeutics

Target Audience

This program is intended for physicians and other HCPs involved in the care of patients with PBC.

Program Learning Goal

The goal of this activity is to improve learners’ competence in translating the most clinically significant data from AASLD 2023 into practical management strategies for patients with PBC.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Incorporate the results of recent clinical studies of PBC screening and management into clinical practice

  • Describe emerging agents for PBC, including mechanism of action, clinical data for both biochemical and symptom response, safety, and potential place in therapy

Disclosure

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvement or quality in healthcare and not a specific proprietary business interest of an ineligible company. 

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Kris V. Kowdley, MD, FAASLD, FACP, FACG

Professor, Elson S. Floyd College of Medicine
Washington State University
Director, Liver Institute Northwest
Seattle, Washington

Kris V. Kowdley, MD, FAASLD, FACP, FACG : consultant/advisor/speaker: 89Bio, AbbVie, BI, CymaBay, Genfit, Gilead, HighTide, Intercept, Ipsen, Kowa, Madrigal, Mirum, NGM NovoNordisk, Pliant, Pfizer, Terns, Zydus; researcher: 89Bio, Boston Pharma, Corcept, CymaBay, Genfit, Gilead, GlaxoSmithKline, Hanmi, HighTide, Intercept, Madrigal, Mirum, NGM, NovoNordisk, Pfizer, Pliant, Terns, Viking, Zydus; royalties or patent beneficiary: UpToDate.

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.25 hours. To successfully complete this activity and receive credit, learners must follow these steps during the period from December 20, 2023, through December 19, 2024:

  1. Login or Sign Up for an account by clicking at the top of this page
  2. Read the target audience, learning objectives, and faculty disclosures
  3. View and study the content in its entirety
  4. Submit answers to the post-test questions and evaluation questions online

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 

Physician Continuing Medical Education
CCO designates this enduring material for a maximum of 0.25 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.