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Improving AATD care with early diagnosis and management

CE / CME

Improving AATD Care Through Early Diagnosis and Multidisciplinary Management: A Call to Action

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Nurse Practitioners/Nurses: 1.00 Nursing contact hour

Physicians: maximum of 1.00 AMA PRA Category 1 Credit

Released: June 12, 2025

Expiration: June 11, 2026

Pretest

Progress
1 2 3
Course Completed
Please answer the questions below.
1.

Based on current guidelines, which of the following patients should be screened for alpha-1 antitrypsin deficiency (AATD)?

2.

A 38-year-old man who smokes tobacco presents with dyspnea on exertion and wheezing. Spirometry reveals a forced expiratory volume (FEV1)/FVC ratio of 0.60, consistent with obstructive lung disease. A chest X-ray shows basal emphysema. Which of the following is the most appropriate next step to confirm a diagnosis of AATD?

3.

A 50-year-old woman with AATD and moderate COPD (FEV1 55% predicted) presents for follow-up. She is a former smoker and reports increased dyspnea despite using a long-acting beta-agonist and an inhaled corticosteroid. Which of the following is the most appropriate next step in developing an individualized management strategy for this patient?

4.

Which of the following statements regarding the current evidence for fazirsiran is most accurate?