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Individualizing ART With Cardiometabolic Considerations

Text Module

Learn the latest on the association between INSTIs, weight gain, and cardiovascular risk by reviewing this expert-led case study. Topics include weight gain assessment in people living with HIV on ART, important cardiometabolic considerations, and the recently updated guidelines on starting statin therapy.

Nurses: 0.75 Nursing contact hour

Pharmacists: 0.75 contact hour (0.075 CEUs)

Physicians: maximum of 0.75 AMA PRA Category 1 Credit

Released: July 10, 2024

Expiration: July 09, 2025



Grace A McComsey

Grace A McComsey, MD

Professor of Medicine and Pediatrics
Vice Dean for Clinical and Translational Research
Case Western Reserve University
Cleveland, Ohio

Provided by

Provided by Clinical Care Options, LLC, in partnership with HIV-ASSIST

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Supported by an educational grant from ViiV Healthcare.

ViiV Healthcare



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Target Audience

This program is intended for physicians, pharmacists, nurses and other healthcare professionals who are involved in the provision of antiretroviral therapy for people living with HIV.

Program Learning Goal

The goal of this program is to enhance learners’ competence in making optimal, evidence-based antiretroviral treatment strategies in specific scenarios where many HIV treaters currently make suboptimal decisions

Learning Objectives

Upon completion of this activity, participants should be able to: 

  • Select an appropriate initial ART regimen for individual people living with HIV


Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Grace A McComsey, MD

Professor of Medicine and Pediatrics
Vice Dean for Clinical and Translational Research
Case Western Reserve University
Cleveland, Ohio

Grace A. McComsey, MD: consultant/advisor/speaker: Gilead, Janssen, ViiV.

The planners and content peer reviewers from Clinical Care Options, LLC and HIV-ASSIST do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.75 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from July 10, 2024, through July 09, 2025:

  1. Login or Sign Up for an account by clicking at the top of this page.
  2. Read the target audience, learning objectives, and faculty disclosures.
  3. View and study the content in its entirety.
  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.


This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by Clinical Care Options, LLC (CCO) and HIV-ASSIST. Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

CCO designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.75 contact hours.

Continuing Pharmacy Education

CCO designates this continuing education activity for 0.75 contact hours (0.075 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number - JA4008176-9999-24-154-H02-

Type of Activity: Application

Upon successfully completing the post-test with a score of 65% or better and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

CME Passport

The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit to create your account.