Foundational Overview of HDV

CE / CME

Hepatitis Delta in Focus: A Foundational Overview of HDV

Pharmacists: 0.75 contact hour (0.075 CEUs)

Nurses: 0.75 Nursing contact hour

Physicians: Maximum of 0.75 AMA PRA Category 1 Credit

Released: December 09, 2022

Expiration: December 08, 2023

Activity

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In this module, Nancy Reau, MD, discusses the burden of hepatitis delta virus (HDV) disease, its impact on liver disease progression, populations at risk, strategies on screening and diagnosing HDV and treatment options including evolving data on future options.

Key points discussed in this module are illustrated with thumbnails from the accompanying downloadable PowerPoint slideset, which can be downloaded here or by clicking any of the slide thumbnails in the module alongside the expert commentary.

Clinical Care Options plans to measure the educational impact of this activity. A question will be asked twice: once at the beginning of the activity and then again after the discussion that informs the best choice. Your responses will be aggregated for analysis, and your specific responses will not be shared.

Before continuing with this educational activity, please take a moment to answer the following questions.

For those providing patient care, how many patients with HDV infection do you provide care for in a typical month?

Following a positive test for anti-HDV antibodies in a person who is hepatitis B surface antigen (HBsAg) positive, what would be the next step to confirm HDV infection?
Patient Case: Introduction

Let us open with a case to help put things in context.

This is a 41-year-old Mongolian woman who has no known significant past medical history. She is not taking any medications. She is referred to the hepatitis clinic because of an increase in liver enzymes, but her hepatic function is still very good.

On physical examination, she looks like a healthy individual. A right upper quadrant ultrasound is obtained that shows course echotexture and the suggestion of nodularity but no masses.

Additional blood tests are ordered, checking for viral hepatitis and markers for possible autoimmune disease such as an antinuclear antibody and a smooth muscle antibody.

Her immune markers return negative, but she has evidence of hepatitis B virus (HBV) exposure with a positive HBsAg.