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IMPALA Subanalysis: Risk of de novo HBV Infection in Nonimmune People With HIV Using LA CAB + RPV ART

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In this subanalysis of the IMPALA study comparing a switch to LA CAB + RPV vs DTG + 2 NRTIs among people with or at risk of suboptimal HIV control in sub-Saharan Africa, there were no cases of HBV reactivation, but 1 case of incident HBV infection occurred in the LA ART arm.

Released: July 17, 2025

Expiration: January 16, 2026

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Provided by Clinical Care Options, LLC in partnership with the International AIDS Society

 
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Supported by educational grants from Gilead Sciences, Inc., Merck & Co., Inc., Rahway, NJ, USA, and ViiV Healthcare.

Gilead Sciences, Inc.

Merck & Co., Inc., Rahway, NJ, USA

ViiV Healthcare

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