NDM Treatment
NDM-Producing Enterobacterales: Applying Best Practices in Complex Clinical Scenarios

Released: November 16, 2023

Emily Heil
Emily Heil, PharmD, MS, BCIDP, AAHIVP
Trevor Van Schooneveld
Trevor Van Schooneveld, MD, FSHEA, FACP
Laila Woc-Colburn
Laila Woc-Colburn, MD

Activity

Progress
1
Course Completed

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections caused by NDM-producing Enterobacterales, including:

  • Ambler classification of β-lactamases
  • Mechanisms of resistance
  • 2023 IDSA guidance recommendations
  • The latest clinical data by antimicrobial regimen:
    • Ceftazidime/avibactam and aztreonam
    • Cefiderocol
    • Investigational aztreonam/avibactam
  • Clinical case of NDM-producing E. coli with pan-β-lactam resistance