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Augmentation in Family Medicine

CE / CME

The Family Medicine Psychiatry Toolkit: Modern Augmentation Strategies for Depression

ABIM MOC: maximum of 1.50 Medical Knowledge MOC points

Pharmacists: 1.50 contact hours (0.15 CEUs)

Nurse Practitioners/Nurses: 1.50 Nursing contact hours

Physicians: maximum of 1.50 AMA PRA Category 1 Credits

Released: November 05, 2025

Expiration: November 04, 2026

Pretest

Progress
1 2 3
Course Completed
Please answer the questions below.
1.

A 45-yr-old man with MDD has been receiving fluoxetine 40 mg/day for 10 wk. He reports a 35% improvement on PHQ-9. He has residual symptoms of low energy and anhedonia. He has demonstrated a partial response to SSRIs in previous episodes. What would be a reasonable next step?

2.

A 43-yr-old woman with MDD has failed a previous trial of sertraline 200 mg/day for 8 wk. She is now is receiving venlafaxine 150 mg with a 35% improvement on the MADRs at 6 wk. What would be a reasonable next step?

3.

A 57-yr-old man has failed 2 previous SSRI trials and is currently on vortioxetine 20 mg. He has a 40% improvement in his PHQ-9 after 8 wk. However, he continues to suffer from severe anxiety and anhedonia. He has a BMI of 41. Of those listed here, what would be the best augmentation strategy?