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Paradoxical Pain: Opioid-Induced Hyperalgesia

Clinical Thought

Even when receiving chronic opioid treatment for pain management, many patients continue to have significant pain and heightened pain sensitivity. After ruling out a worsening of the underlying condition, healthcare professionals should include opioid-induced hyperalgesia in their differential. Read this clinical commentary to learn more about recognizing and managing opioid-induced hyperalgesia.

Released: May 30, 2023

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Faculty

Andrew Friedman

Andrew Friedman, MD

Section Head
Virginia Mason Medical Center
Medical Director
Virginia Mason Franciscan Health
Clinical Assistant Professor
University of Washington
Seattle, Washington

Provided by

Provided by Clinical Care Options, LLC, and in partnership with the American Academy of Physical Medicine and Rehabilitation, Alliance to Advance Comprehensive Integrative Pain Management, Practicing Clinicians Exchange, and ProCE.

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Supporters

This activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies. Please see this link for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the FDA.

Opioid Analgesic REMS Program Companies

Partners

Alliance to Advance Comprehensive Integrative Pain Management

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American Academy of Physical Medicine and Rehabilitation

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Practicing Clinicians Exchange

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ProCE

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Disclosure

Primary Author

Andrew Friedman, MD

Section Head
Virginia Mason Medical Center
Medical Director
Virginia Mason Franciscan Health
Clinical Assistant Professor
University of Washington
Seattle, Washington

Andrew Friedman, MD, has no relevant financial relationships to disclose.