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PrEP: Fulfilling the Promise of Current and Future Regimens

Text Module

Learn how current PrEP regimens represent a revolutionary step forward in enabling many individuals to avoid HIV acquisition, about barriers that have prevented the full potential of today’s PrEP regimens from being delivered, how those barriers might be overcome, and how the next generation of PrEP modalities may address unmet needs and take us closer to a future without HIV.

Nurses: 0.75 Nursing contact hour

Physicians: maximum of 0.75 AMA PRA Category 1 Credit

Pharmacists: 0.75 contact hour (0.075 CEUs)

Released: November 20, 2023

Expiration: November 19, 2024



Linda-Gail Bekker

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD

CEO, Desmond Tutu Health Foundation
Director, Desmond Tutu HIV Centre
Professor of Medicine
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Provided by

Provided by Clinical Care Options, LLC.

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Supported by an educational grant from Gilead Sciences, Inc.

Gilead Sciences, Inc.

Target Audience

This program is intended for physicians, pharmacists, registered nurses, and other healthcare professionals who care for persons at risk of HIV acquisition.

Program Learning Goal

The goal of this program is to improve learners’ knowledge and competence regarding the evolving field of HIV PrEP regimens and guideline-based recommendations.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Select the optimal current PrEP regimen for each patient that will maximize adherence, tolerability, and HIV prevention outcomes based on patient and regimen characteristics

  • Identify characteristics of current PrEP regimens that may limit their utility for specific patients and/or in specific healthcare settings

  • Assess the potential for emerging PrEP modalities to meet currently unmet patient needs based on their dosage forms, administration protocols, safety profiles, and/or efficacy


Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Program Director

Linda-Gail Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD

CEO, Desmond Tutu Health Foundation
Director, Desmond Tutu HIV Centre
Professor of Medicine
Faculty of Health Sciences
University of Cape Town
Cape Town, South Africa

Linda Gail-Bekker, MBChB, DTM&H, DCH, FCP(SA), PhD: consultant/advisor/speaker: Gilead, Janssen, Johnson & Johnson, Merck, ViiV. 

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.75 hours. To successfully complete this activity and receive credit, learners must follow these steps during the period from November 20, 2023, through November 19, 2024:

  1. Login or Sign Up for an account by clicking at the top of this page
  2. Read the target audience, learning objectives, and faculty disclosures
  3. View and study the content in its entirety
  4. Submit answers to the post-test questions and evaluation questions online

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.


This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


Joint Accreditation Statement
Joint AccreditationIn support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 


Physician Continuing Medical Education

CCO designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development
The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.75 contact hours.

Continuing Pharmacy Education

CCO designates this continuing education activity for 0.75 contact hours (0.075 CEUs) of the Accreditation Council for Pharmacy Education.

Universal Activity Number - JA4008176-0000-23-302-H02-P
Type of Activity: Knowledge

Upon successfully completing the post-test with a score of 65 or better and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.