Adv Endometrial Cancer SoC

CE / CME

Current Standard of Care for Advanced Endometrial Cancer

ABIM MOC: maximum of 1.00 Medical Knowledge MOC point

Physicians: Maximum of 1.00 AMA PRA Category 1 Credit

Released: September 07, 2023

Expiration: September 06, 2024

Lauren Prescott
Lauren Prescott, MD, MPH
Ritu Salani
Ritu Salani, MD, MBA

Activity

Progress
1
Course Completed

Introduction

In this module, Lauren Prescott, MD, MPH, discusses the evidence informing the recent changes in the standard of care (SoC) for newly diagnosed and recurrent advanced‑stage endometrial cancer.

The key points discussed in this module are illustrated with thumbnails from the accompanying downloadable PowerPoint slideset that can be found here or downloaded by clicking any of the slide thumbnails in the module alongside the expert commentary.

Clinical Care Options plans to measure the educational impact of this activity. One question will be asked twice: once at the beginning of the activity and then once again after the discussion that informs the best choice. Your responses will be aggregated for analysis, and your specific responses will not be shared.

Before continuing with this educational activity, please take a moment to answer the following questions.

For those providing patient care, how many patients with endometrial cancer do you provide care for in a typical month?

Your patient presents for a second opinion on systemic treatment of her newly diagnosed stage IVB, grade 3 uterine carcinosarcoma with liver and lung metastases. Immunohistochemistry (IHC) of her initial biopsy shows aberrant p53, no alteration detected in HER2, and MLH1 and PMS2 protein loss.

In your current practice, which of the following systemic treatment options would you consider to be the optimal choice for this patient?