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CDK46 Inhibitors in Breast Cancer

CE / CME

CDK4/6 Inhibitors in HR-Positive/HER2-Negative Breast Cancer: Experts Answer Your Questions

ABIM MOC: maximum of 0.25 Medical Knowledge MOC point

Physician Assistants: maximum of 0.25 hour of AAPA Category 1 CME credit

Registered Nurses: 0.25 Nursing contact hour

Pharmacists: 0.25 contact hour (0.025 CEUs)

Physicians: maximum of 0.25 AMA PRA Category 1 Credit

Released: August 13, 2025

Expiration: February 12, 2026

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Please answer the questions below.
1.

Which of the following is optimal management for a patient receiving adjuvant abemaciclib for stage IIIA hormone receptor–positive/HER2-negative breast cancer with an elevated serum creatinine?