First-line Data for ROS1-Altered Advanced NSCLC
Available Clinical Data and Approved First-line Treatments for ROS1-Altered Advanced NSCLC

Released: September 05, 2024

Expiration: September 04, 2025

Jessica J Lin
Jessica J Lin, MD
Alice Shaw
Alice Shaw, MD, PhD

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In this episode, listen to Alice T. Shaw, MD, PhD, and Jessica J. Lin, MD, share their thoughts on the available clinical data in support of frontline treatments for ROS1-altered NSCLC including:

  • Efficacy and safety data for crizotinib, entrectinib, and repotrectinib in patients with ROS1-altered advanced NSCLC
  • Long-term safety observations for crizotinib and entrectinib
  • CNS activity of entrectinib and repotrectinib in patients with brain metastases
  • Repotrectinib activity in ROS1-TKI resistance mutations