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GAIN: Phase III Trial of (Neo)Adjuvant Chemotherapy and Radical Liver Resection vs Radical Liver Resection Alone ± Adjuvant Therapy in BTC

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Final results from the phase III GAIN trial demonstrate statistically significant and clinically meaningful improvements in OS and EFS with neoadjuvant chemotherapy vs surgery alone with or without adjuvant chemotherapy for patients with biliary tract cancer.

Released: June 09, 2025

Expiration: December 08, 2025

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Provided by Clinical Care Options, LLC

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Supported by educational grants from Daiichi Sankyo, Inc. and Genentech, a member of the Roche Group.

Daiichi Sankyo, Inc.

Genentech, a member of the Roche Group