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Answers to Your Questions on the Evolving Treatment Paradigm in SCLC

Clinical Thought

Read expert responses to your frequently asked questions to gain practical insights on the changing treatment landscape for patients with limited-stage or extensive-stage SCLC.

Released: July 22, 2025

Expiration: January 21, 2026

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Provided by Clinical Care Options, LLC.

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Supported by educational grants from Amgen, Daiichi Sankyo, Inc., Jazz Pharmaceuticals, Inc. and Merck Sharp & Dohme LLC.

Amgen

Daiichi Sankyo, Inc.

Jazz Pharmaceuticals, Inc.

Merck Sharp & Dohme, LLC

Disclosure

Primary Author

Melissa L. Johnson, MD: researcher (paid to institution): Adaptimmune, Amgen, ArriVent, AstraZeneca, Bayer, Black Diamond, BlossomHill, Boehringer Ingelheim, Boundless Bio, Bristol Myers Squibb, Carisma, Conjupro Biotherapeutics, Corvus, D3 Bio, Daiichi Sankyo, Erasca, Exelixis, Genentech/Roche, Genmab, Genocea, Harpoon, Helsinn Healthcare SA, IDEAYA, IGM, Immuneering, Immunitas, Immunocore, Incyte, Janssen, Lilly, Lockbody, Loxo Oncology, Merck, Merus, Mirati, Modex, Mythic, NeoImmune Tech, Neovia Oncology, NextPoint, Novartis, Nuvalent, OncoC4, Palleon, Pfizer, Pierre Fabre, PMV Pharmaceuticals, Prelude, Puma Biotechnology, RasCal, Regeneron, Revolution Medicines, Ribon, Shattuck Labs, Shanghai Junshi Biosciences, Silicon, Summit, Systimmune, Taiho Oncology, TCR2, Tempest, TheRas, Tizona, Vividion, Zymeworks; consultant/advisor/speaker (paid to institution): AbbVie, Alentis, Amgen, Arcus Biosciences, AstraZeneca, BeOne Medicines, Biohaven, Boehringer Ingelheim, Bristol Myers Squibb, D3 Bio Limited, Daiichi Sankyo, Fate, Genentech/Roche, Gilead Sciences, GlaxoSmithKline, Hookipa Biotech, Janssen, Jazz, Lilly, Merck, Mirati, ModeX, Normunity, Novartis, Novocure, Pfizer, Regeneron, Revolution Medicines, Takeda, Zai Laboratory.

Ticiana Leal, MD: consultant/advisor/speaker: AbbVie, Amgen, AstraZeneca, Black Diamond, Boehringer Ingelheim, Bristol Myers Squibb, Catalyst, Genentech, Gilead, Jazz, Johnson & Johnson, Novocure, OncoC4, Pfizer, Regeneron, Roche, Summit Therapeutics, Synthekine; researcher (paid to institution): AstraZeneca, Boehringer Ingelheim, Daiichi Sankyo, Nuvalent, Prelude, Synthekine.

Mark A. Socinski, MD: consultant/advisor/speaker: AstraZeneca, BeiGene, Bristol Myers Squibb, Genentech, Guardant, Janssen, Jazz, Merck, Spectrum, Summit; researcher: AstraZeneca, BeiGene, Enliven, Spectrum.