Faculty

Alexander E. Drilon, MD

Chief, Early Drug Development Service
Memorial Sloan Kettering Cancer Center
New York, New York

Laura J. Tafe, MD

Associate Professor of Pathology and Laboratory Medicine
Associate Director, Laboratory for Clinical Genomics and Advanced Technology and Director of Molecular Oncology
Dartmouth-Hitchcock Medical Center and the Geisel School of Medicine
Lebanon, New Hampshire

Provided by

Provided by Clinical Care Options, LLC, in partnership with Q Synthesis and the Association for Molecular Pathology

Supporters

This activity is supported by an educational grant from Lilly.

Lilly

Partners

AMP

Q Synthesis LLC

Target Audience

Oncologists, pathologists, nurse practitioners, physician associates, pharmacists, and other healthcare professionals who manage patients with cancer within 3 community and academic cancer centers.

Program Learning Goal

The overall initiative aim by the conclusion of this project is to improve clinical outcomes in patients with advanced solid tumors harboring actionable biomarkers among participating clinic sites.

Learning Objectives

Upon completion of this activity, participants should be able to:

Accurately interpret molecular pathology results to select appropriate targeted therapies for patients with advanced solid tumors prior to initiating therapy
Communicate the rationale for molecular testing to patients and its critical value in determining their treatment plans
Select and sequence individualized genomic alteration–directed targeted therapy for patients with solid tumors based on current evidence, guidelines, expert recommendations, and tumor molecular profile

Disclosure

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Alexander E. Drilon, MD

Chief, Early Drug Development Service
Memorial Sloan Kettering Cancer Center
New York, New York

Alexander E. Drilon, MD: honoraria: 14ner/Elevation Oncology, Bristol Myers Squibb, EcoR1, Ignyta/Genentech/Roche, Loxo/Bayer/Lilly, Novartis, Pfizer, Prelude, Regeneron, Treeline Bio, Verastem, Zymeworks; advisory boards: AbbVie, Amgen, AnHeart Therapeutics, Bayer, EcoR1, Loxo/Lilly, Monte Rosa, Novartis; consulting: 14ner/Elevation Oncology, Boundless Bio, Innocare, Monte Rosa, Treeline Bio; research: Foundation Medicine, GlaxoSmithKline, PharmaMar, Taiho, Teva; individual publicly traded stock/stock options: MBrace, Treeline; other financial or material support: Boehringer Ingelheim, Merck, Puma.

Laura J. Tafe, MD

Laura J. Tafe, MD, has no relevant financial relationships to disclose.

The planners and content peer reviewers from Clinical Care Options, LLC, Q Synthesis, and the Association for Molecular Pathology do not have any relevant financial relationships to disclose, except Kristi K. Orbaugh, MSN, RNP, AOCNP, as noted below.

Kristi K. Orbaugh, MSN, RNP, AOCNP: consultant/advisor/speaker: AstraZeneca, Bristol Myers Squibb, Daichii Sankyo, Eli Lilly, Gilead, Pfizer, Regeneron, SOBI.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.25 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from September 13, 2024, through September 12, 2025:

Login or Sign Up for an account by clicking at the top of this page.
Read the target audience, learning objectives, and faculty disclosures.
View and study the content in its entirety.
Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by Clinical Care Options, LLC (CCO), Q Synthesis, and the Association for Molecular Pathology. Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

CCO designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.25 contact hours.

Continuing Pharmacy Education

CCO designates this continuing education activity for 0.25 contact hours (0.025 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number - JA4008176-9999-24-229-H01-P

Type of Activity: Knowledge

Upon successfully completing the post-test with a score of 65% or better and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

Physician Associate Continuing Medical Education

Clinical Care Options, LLC has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.25 AAPA Category 1 CME credits. Approval is valid until September 12, 2025. PAs should only claim credit commensurate with the extent of their participation.

American Board of Internal Medicine Maintenance of Certification

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

For ABIM MOC points, your information will be shared with the ABIM through CCO’s Joint Accreditation Program and Activity Reporting System (JAPARS). Please allow 6-8 weeks for your MOC points to appear on your ABIM records.

By sharing your Diplomate Board ID # and DOB, you are giving Clinical Care Options, LLC permission to use this information/data to report your participation to these Boards via the Joint Accreditation Program and Activity Reporting System (JA-PARS).

CME for MIPS

Completion of this accredited CME activity meets the expectations of an Accredited Safety or Quality Improvement Program (IA_PSPA_28) for the Merit-based Incentive Payment Program (MIPS).

In order to fulfill requirements for MIPS improvement activity, participants will need to fill out 2 brief follow-up surveys at 30- and 90-days post-activity.

CME Passport

The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit www.cmepassport.org to create your account.

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