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CE / CME

Fundamentals I: Understanding and Differentiating ADCs Targeting HER2, HER3, and TROP2 in Solid Tumors

Video

In this on-demand webcast, an expert discusses the mechanism of action of antibody–drug conjugates (ADCs) and how those directed at HER2, HER3, and TROP2 are being used to manage various solid tumors. 

Physician Assistants/Physician Associates: 0.50 AAPA Category 1 CME credit

Nurse Practitioners: 0.50 Nursing contact hours, includes 0.50 hour of pharmacotherapy credit

Released: December 03, 2024

Expiration: December 02, 2025

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Faculty

Sara Cooper

Sara Cooper, MSN, RN, ACNP-BC, AOCNP-BC

Breast Oncology Nurse Practitioner
MemorialCare Cancer Institute
MemorialCare Medical Group
Orange County, California

Kristi K. Orbaugh

Kristi K. Orbaugh, MSN, RNP, AOCNP

Adult Oncology Nurse Practitioner
Community Hospital Oncology Physician
A Partner of MD Anderson
Indianapolis, Indiana

Kimberly Podsada

Kimberly Podsada, MSN, NP-C

Oncology Nurse Practitioner
UCSD Comprehensive Breast Health Center
La Jolla, California

Provided by

Provided by Partners for Advancing Clinical Education (PACE) in partnership with Practicing Clinicians Exchange, LLC and Clinical Care Options, LLC

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Supporters

Supported by educational grants from AstraZeneca and Gilead Sciences, Inc.

AstraZeneca

Gilead Sciences, Inc.

Partners

Clinical Care Options, LLC

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Practicing Clinicians Exchange

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Target Audience

This activity is intended for nurse practitioners, physician associates, clinical nurse specialists, and advanced degree nurses who manage patients treated with HER2-, HER3-, and TROP2-targeted ADCs.

Program Learning Goal

This activity aims to improve learners’ knowledge and competence to optimize outcomes in patients treated with HER2-, HER3-, and TROP2-targeted ADCs.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss how structural, mechanistic, and unique characteristics, including the “bystander effect,” of antibody–drug conjugates contribute to differing toxicities and adverse event profiles

Disclosure

PACE requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to PACE policies. Others involved in the planning of this activity have no relevant financial relationships.

Primary Author

Sara Cooper, MSN, RN, ACNP-BC, AOCNP-BC

Breast Oncology Nurse Practitioner
MemorialCare Cancer Institute
MemorialCare Medical Group
Orange County, California

Sara Cooper, MSN, RN, ACNP-BC, AOCNP-BC: consultant/advisor/speaker: Accellapy, AstraZeneca, Lilly, Novartis, Stemline.

Kristi K. Orbaugh, MSN, RNP, AOCNP

Adult Oncology Nurse Practitioner
Community Hospital Oncology Physician
A Partner of MD Anderson
Indianapolis, Indiana

Kristi K. Orbaugh, MSN, RNP, AOCNP: consultant/advisor/speaker: AstraZeneca, Bristol Myers Squibb, Daichii Sankyo, Eli Lilly, Gilead, Pfizer, Regeneron, SOBI.

Kimberly Podsada, MSN, NP-C

Oncology Nurse Practitioner
UCSD Comprehensive Breast Health Center
La Jolla, California

Kimberly Podsada, MSN, NP-C: speaker: AstraZeneca, Daiichi Sankyo, Novartis, Pfizer.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.5 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from December 03, 2024, through December 02, 2025:

  1. Login or Sign Up for an account by clicking at the top of this page.

  2. Read the target audience, learning objectives, and faculty disclosures.

  3. View and study the content in its entirety.

  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, Partners for Advancing Clinical Education (PACE) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. 

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.5 contact hours, including 0.5 hours of pharmacotherapy credit.

Physician Associate Continuing Medical Education

Partners for Advancing Clinical Education (PACE) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.5 AAPA Category 1 CME credits. Approval is valid until December 02, 2025. PAs should only claim credit commensurate with the extent of their participation.

IPCE Credit Designation

This activity was planned by and for the healthcare team, and learners will receive 0.5 Interprofessional Continuing Education (IPCE) credits for learning and change.