Podcast: ART with OIs
Key Decisions in HIV Care: Managing ART With Opportunistic Infections

Released: April 05, 2022

Expiration: April 04, 2023

Cristina Mussini
Cristina Mussini, MD
William R. Short
William R. Short, MD, MPH, FIDSA

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In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss important considerations for ART with opportunistic infections, including:

  • When to start ART with pneumocystis pneumonia including discussion of the ACTG 5164 study of immediate vs delayed ART with opportunistic infections
  • EACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of most opportunistic infections
  • Considerations for the administration of ART to patients who are unable to swallow or critically ill and intubated
  • Treatment of Kaposi sarcoma and considerations for starting ART to avoid drug–drug interactions with Kaposi sarcoma treatment
  • Considerations for starting ART with cytomegalovirus and the risk for IRIS from cytomegalovirus
  • Discussion of treatment of cytomegalovirus and overlapping toxicities between its treatment and ART
  • When to start ART with cryptococcal meningitis and the data to support delayed treatment initiation with this particular opportunistic infection
  • EACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of cryptococcal meningitis specifically
  • Treatment of cryptococcal meningitis and managing drug–drug interactions between ART and antifungal therapy