Podcast: Coinfections
Key Decisions in HIV Care: ART Considerations With Coinfections

Released: January 10, 2022

Expiration: January 09, 2023

Daria Podlekareva
Daria Podlekareva, MD, PhD
Mark S. Sulkowski
Mark S. Sulkowski, MD

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In this episode from the series “Key Decisions in HIV Care,” Daria Podlekareva, MD, PhD, and Mark S. Sulkowski, MD, discuss important considerations for ART use in patients with coinfections, including:

  • DHHS testing and treatment recommendations for HBV in patients with HIV
  • Data suggesting that tenofovir alone may not suppress HBV in all PWH
  • Data from NA-ACCORD showing that incomplete HBV DNA suppression is associated with HCC in patients with HIV/HBV
  • Data for the use of entecavir as an add-on therapy if an HIV ART regimen is not HBV active
  • Data showing that lamivudine alone is associated with resistance in patients with HIV/HBV
  • Discussion of HBV management in the setting of 2-drug regimens for HIV if the patient is coinfected
  • Recommendations from the DHHS, EACS, and WHO to start ART as soon as possible in patients with TB/HIV coinfection
  • Data from the SAPiT, ACTG A5221 STRIDE, and CAMELIA studies to show the benefits of early ART in patients with TB/HIV
  • Recommendations from the EACS guidelines on what ART regimens are recommended with TB/HIV
  • Drug-drug interaction considerations between ART and TB treatment
  • Discussion of the prevention and management of TB-associated IRIS