ProCE Banner Activity


Decoding Complexity: Best Practices in Identifying and Managing Bipolar Depression with DSM-5-TR Specifiers


On-demand webcast of expert faculty presentation and case discussion on identifying and managing patients with bipolar depression using DSM-5-TR specifiers to optimize their care, from CCO’s Psychiatry Summit 2024.

Nurses: 1.00 Nursing contact hour

Pharmacists: 1.00 contact hour (0.1 CEUs)

Physicians: Maximum of 1.00 AMA PRA Category 1 Credit

Released: June 05, 2024

Expiration: June 04, 2025



Roger S. McIntyre

Roger S. McIntyre, MD, FRCPC

Professor of Psychiatry and Pharmacology
University of Toronto, Canada
Toronto, Canada

Provided by

Provided by Clinical Care Options, LLC

ProCE Banner


Supported by an educational grant from Intra-Cellular Therapies, Inc.

Intra-Cellular Therapies, Inc.

Target Audience

This program is intended for healthcare professionals caring for patients with bipolar depression, including physicians (psychiatrists and family medicine/primary care), nurse practitioners, physician associates, registered nurses, and pharmacists.

Program Learning Goal

The goal of this program is to improve the knowledge, competence, and performance of learners to optimize treatment for patients with bipolar depression.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify bipolar depression with DSM-5-TR specifiers based on symptoms and diagnostic criteria

  • Interpret the latest evidence for pharmacologic treatment of bipolar depression in the presence of mixed features or anxious distress

  • Create an individualized treatment plan for patient with bipolar depression in the presence of mixed features or anxious distress


Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Roger S. McIntyre, MD, FRCPC

Professor of Psychiatry and Pharmacology
University of Toronto, Canada
Toronto, Canada

Roger S. McIntyre, MD, FRCPC: speaker/consultant: AbbVie, Alkermes, Atai Life Sciences, Axsome, Bausch Health, Biogen, Boehringer Ingelheim, Eisai, Intra-Cellular, Janssen, Kris, Lundbeck, Mitsubishi Tanabe, Neumora Therapeutics, NeuraWell, Neurocrine, Novo Nordisk, NewBridge, Otsuka, Pfizer, Purdue, Sage, Sanofi, Sunovion, Takeda, Viatris; executive role: Braxia Scientific Corp.

The planners and content peer reviewers from Clinical Care Options, LLC do not have any relevant financial relationships to disclose, except Michael Asbach, DMSc, PA-C, as noted below.​

Michael Asbach, DMSc, PA-Cconsultant/advisor/speaker: AbbVie, Avanir, Intra-Cellular, Janssen, Neurocrine, Otsuka, Sage/Biogen.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 1 hour. To successfully complete this activity and receive credit, participants must follow these steps during the period from June 05, 2024, through June 04, 2025:

  1. Login or Sign Up for an account by clicking at the top of this page.
  2. Read the target audience, learning objectives, and faculty disclosures.
  3. View and study the content in its entirety.
  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.


This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

CCO designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1 contact hour.

Continuing Pharmacy Education

CCO designates this continuing education activity for 1 contact hour (0.1 CEUs) of the Accreditation Council for Pharmacy Education.
Universal Activity Number - JA4008176-0000-24-136-H01-P

Type of Activity: Application

Upon successfully completing the post-test with a score of 65% or better and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

ABMS Approval Statement

Through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, Calming The Storm: Understanding and Managing Agitation in Alzheimer’s-Disease; Decoding Complexity: Best Practices in Identifying and Managing Bipolar Depression with DSM-5-TR Specifiers, has met the requirements as a Lifelong Learning CME Activity (apply toward general CME requirement) for the following ABMS Member Boards: 

ABMS Lifelong Learning CME Activity
Family Medicine
Psychiatry and Neurology

CME Passport 


The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit to create your account.