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CAPTIVATE MRD Cohort: 2-Yr Postrandomization Efficacy and Safety With First-Line Ibrutinib + Venetoclax in CLL

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Initial therapy with ibrutinib + venetoclax for 12 cycles resulted in a 2-year DFS rate of 95.3% in patients with undetectable MRD who were subsequently randomized to placebo and 100% in those subsequently randomized to ibrutinib.

Released: December 21, 2021

Expiration: December 20, 2022

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AbbVie

AstraZeneca

Daiichi Sankyo, Inc.

GlaxoSmithKline

Incyte Corporation

Jazz Pharmaceuticals, Inc.

Merck Sharp & Dohme Corp.

Novartis Pharmaceuticals Corporation