Test Your Skills: Medullary Thyroid Cancer

CE / CME

Test Your Skills: Understanding the Current Biomarker Landscape for Patients With Medullary Thyroid Cancer

Physician Assistants/Physician Associates: 0.25 AAPA Category 1 CME credit

Nurses: 0.25 Nursing contact hour

Pharmacists: 0.25 contact hour (0.025 CEUs)

Physicians: maximum of 0.25 AMA PRA Category 1 Credit

ABIM MOC: maximum of 0.25 Medical Knowledge MOC point

Released: September 17, 2024

Expiration: September 16, 2025

Activity

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Follow-up—Case Continued
A formalin-fixed, paraffin-embedded thyroid tissue sample was sent for testing using DNA-based and RNA-based NGS along with PD-L1 immunohistochemistry. The use of NGS allows for comprehensive analysis of multiple genes relevant to MTC. The patient’s NGS report indicates the presence of specific molecular alterations.

When reviewing an NGS report, which of the following genomic alterations would you use to guide therapy for a patient with recurrent MTC?