MDD Treatment Augmentation

CME

Guidelines Overview: Augmentation Therapies in Major Depressive Disorder

Physicians: Maximum of 1.00 AMA PRA Category 1 Credit

Released: February 26, 2020

Expiration: February 25, 2021

Activity

Progress
1
Course Completed

References

  1. Hasin DS, Sarvet AL, Meyers JL, et al. Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States. JAMA Psychiatry. 2018;75:336-346.
  2. Greenberg PE, Fournier AA, Sisitsky T, et al. The economic burden of adults with major depressive disorder in the United States (2005 and 2010). J Clin Psychiatry. 2015;76:155-162.
  3. Goodwin GM. Depression and associated physical diseases and symptoms. Dialogues Clin Neurosci. 2006;8:259-265.
  4. Gilman SE, Sucha E, Kingsbury M, et al. Depression and mortality in a longitudinal study: 1952-2011. CMAJ. 2017;189:E1304-E1310.
  5. Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006;163:1905-1917.

  6. McIntyre RS, Fallu A, Konarski JZ. Measurable outcomes in psychiatric disorders: remission as a marker of wellness. Clin Ther. 2006;28:1882-1891.
  7. Zimmerman M, Posternak MA, Chelminski I. Derivation of a definition of remission on the Montgomery-Asberg depression rating scale corresponding to the definition of remission on the Hamilton rating scale for depression. J Psychiatr Res. 2004;38:577-582.
  8. American Psychiatric Association. Practice Guideline for the Treatment of Patients With Major Depressive Disorder, 3rd ed. Washington, DC: American Psychicatric Association; 2010.
  9. Lam RW, McIntosh D, Wang J, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 1. Disease Burden and Principles of Care. Can J Psychiatry. 2016;61:510-523.
  10. 2019-2020 Florida Best Practice Psychotherapeutic Medication Guidelines for Adults. Agency for Health Care Administration, State of Florida, 2020. Available at: http://www.medicaidmentalhealth.org/_assets/file/Guidelines/2019%20Psychotherapeutic%20Medication%20Guidelines%20for%20Adults%20with%20References.pdf. Accessed February 11, 2020.
  11. Aripiprazole package insert. Tokyo, Japan: Otsuka Pharmaceutical; 2019.
  12. Brexpiprazole package insert. Tokyo, Japan: Otsuka Pharmaceutical; 2018.
  13. Quetiapine XR package insert. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2018.
  14. Olanzapine/fluoxetine package insert. Indianapolis, IN: Eli Lily and Company; 2009.
  15. Esketamine nasal spray package insert. Titusville, NJ: Janssen Pharmaceuticals; 2019.