FAQ Module: Diagnosis/Transmission
Frequently Asked Questions on Diagnosis, Transmission, and Epidemiology of SARS-CoV-2

Released: July 08, 2020

Expiration: July 07, 2021

David Heymann
David Heymann, BA, MD, DTM&H
Sharon R. Lewin
Sharon R. Lewin, AO, FRACP, PhD, FAHMS
Jens D. Lundgren
Jens D. Lundgren, MD, DMSc
Vikramjit Mukherjee
Vikramjit Mukherjee, MD
Roger Paredes
Roger Paredes, MD, PhD
Lynora Saxinger
Lynora Saxinger, MD, FRCPC, CTropMed
Leo Yee-Sin
Leo Yee-Sin, MBBS, MPH, MRCP, FRCP, FAMS

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References

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Plante JA, Liu Y, Liu J, et al. Spike mutation D614G alters SARS-CoV-2 fitness. Nature. 2021;592:116-121.

Pollán M, Pérez-Gómez B, Pastor-Barriuso R, et al. Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study. Lancet. 2020;396:535.

Premraj A, Aleyas AG, Nautiyal B, et al. Nucleic Acid and Immunological Diagnostics for SARS-CoV-2: Processes, Platforms and Pitfalls. Diagnostics (Basel). 2020;10:866.

Public Health Agency of Canada. Public health management of cases and contacts associated with COVID-19. Updated December 23, 2020. Available at: https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/health-professionals/interim-guidance-cases-contacts.html. Accessed April 4, 2021.

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Robbiani DF, Gaebler C, Muecksch F, et al. Convergent antibody responses to SARS-CoV-2 in convalescent individuals. Nature. 2020;584:437-442.

Rostami A, Sepidarkish M, Leeflang MMG, et al. SARS-CoV-2 seroprevalence worldwide: a systematic review and meta-analysis. Clin Microbiol Infect. 2020;27:331-340.

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Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. 2020b;323:1843-1844

Ward H, Cooke G, Atchison C, et al. Declining prevalence of antibody positivity to SARS-CoV-2: a community study of 365,000 adults. medRxiv. October 27, 2020. Available at: https://www.medrxiv.org/content/10.1101/2020.10.26.20219725v1. Accessed April 4, 2021.

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Xiao F, Sun J, Xu Y, et al. Infectious SARS-CoV-2 in Feces of Patient with Severe COVID-19. Emerg Infect Dis. 2020;26:1920-1922.

Yang Y, Yang M, Shen C, et al. Evaluating the accuracy of different respiratory specimens in the laboratory diagnosis and monitoring the viral shedding of 2019-nCoV infections. medRxiv. 2020;Preprint. Note: This study has not been peer reviewed.

Young BE, Fong SW, Chan YH, et al. Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study. Lancet. 2020;396:603-611.